Actively Recruiting
Denervation for Osteoarthritis in the PIP-joint Efficacy Study (DOPS)
Led by Karolinska Institutet · Updated on 2024-12-02
90
Participants Needed
1
Research Sites
302 weeks
Total Duration
On this page
Sponsors
K
Karolinska Institutet
Lead Sponsor
S
Stockholm South General Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to compare the effects of a surgical and a non-surgical treatment method in patients with osteoarthritis in the proximal interphalangeal (PIP) joint. The main questions it aims to answer are: * Are the treatments effective? * Is the surgical treatment more effective than the non-surgical treatment? Participants will receive surgical treatment (PIP joint denervation) or non surgical treatment (patient education plus exercise). Researchers will compare the non-surgical and surgical groups to see if pain, patient-reported function, quality of life, movement and grip strength differs between the groups.
CONDITIONS
Official Title
Denervation for Osteoarthritis in the PIP-joint Efficacy Study (DOPS)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 63 18 years
- Chronic symptomatic osteoarthritis in the PIP-joint
- Radiological signs of osteoarthritis on posteroanterior and lateral radiographs assessed by the Kellgren-Lawrence classification (grade II-IV)
- Clinical signs of PIP-joint arthritis
You will not qualify if you...
- Inflammatory arthritis
- Ongoing infection in the hand
- Inability to co-operate with the follow-up protocol
- Intra-articular glucocorticoid, PRP or Hyaluronic acid injections in the affected joint less than 3 months prior to enrollment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Department of Hand Surgery, Södersjukhuset
Stockholm, Sweden
Actively Recruiting
Research Team
E
Elin Sward, MD, PhD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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