Actively Recruiting

Age: 12Years - 18Years
All Genders
NCT06506734

Dental Dyschromia and Quality of Life in Early Prolonged Hyperbilirubinemia

Led by University Hospital, Toulouse · Updated on 2026-05-12

120

Participants Needed

9

Research Sites

78 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The main objective of this study is to assess the prevalence of dental discoloration (dental dyschromia) in children who experienced high levels of bilirubin in their blood (hyperbilirubinemia) during their early years. The study will also examine risk factors associated with this condition, such as the duration and severity of hyperbilirubinemia, underlying diseases, and treatments received. The researchers hypothesize that the quality of life of individuals with dental dyschromia is lower than that of individuals without dyschromia. The results of this study will be used to discuss coverage for dental care with health insurance for children affected by this condition.

CONDITIONS

Official Title

Dental Dyschromia and Quality of Life in Early Prolonged Hyperbilirubinemia

Who Can Participate

Age: 12Years - 18Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient with biliary atresia, progressive familial intrahepatic cholestasis, or Alagille syndrome
  • Patient or legal representative not opposed to participating in this research
Not Eligible

You will not qualify if you...

  • Inability to understand and respond to quality of life questionnaires

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 9 locations

1

University Hospital Bordeaux

Bordeaux, France

Actively Recruiting

2

University Hosptial Caen

Caen, France

Actively Recruiting

3

University Hospital Lille

Lille, France

Actively Recruiting

4

Hospices Civils de Lyon

Lyon, France

Actively Recruiting

5

University Hospital Marseille

Marseille, France

Actively Recruiting

6

Assistance Publique-Hôpitaux de Paris, Hôpital Bicêtre, FHU Hépatinov

Paris, France

Actively Recruiting

7

Assistance Publique-Hôpitaux de Paris, Hôpital Bretonneau, Paris

Paris, France

Actively Recruiting

8

Assistance Publique-Hôpitaux de Paris, Hôpital Necker

Paris, France

Actively Recruiting

9

University Hospital Rennes

Rennes, France

Actively Recruiting

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Research Team

N

Nolwenn LABORDE, MD

CONTACT

R

Romain LOPEZ, PharmD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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