Actively Recruiting

Age: 55Years - 75Years
All Genders
ID06690385

Registry of Patients Included in the DEPRECAP Lung Cancer Screening Programme by Low-dose CT for Patients With COPD or Emphysema

Led by Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz · Updated on 2024-11-15

1998

Participants Needed

2

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are conducting the DEPRECAP study, a long-term observational program focused on lung cancer screening in people with COPD or emphysema. This study aims to gather scientific evidence about the benefits and potential effects of lung cancer screening using low-dose CT scans in this high-risk group. It also seeks to address under-diagnosis of COPD and encourage smoking cessation to reduce deaths from late-stage lung cancer. Participants in this study undergo annual low-dose CT scans and lung function tests until they reach 75 years of age or have abstained from smoking for 15 years, whichever comes first. The study collects clinical, radiological, and biological data to create a registry for future research. It includes current and former smokers with significant smoking history and diagnosed COPD or emphysema. Those who join will be monitored through yearly evaluations including imaging and pulmonary tests. Researchers will measure outcomes related to lung cancer detection and smoking cessation over a 15-year period. The study is designed to follow participants closely to better understand long-term effects of screening and smoking habits on lung health and cancer risks.

CONDITIONS

Brief Title

DEPRECAP: Lung Cancer Screening Programme by LDCT for Patients With COPD or Emphysema.

Who Can Participate

Age: 55Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Current or former smokers with less than 15 years since quitting
  • Smoking history of more than 30 pack-years
  • Diagnosis of COPD according to GOLD guidelines and/or emphysema identified by low-dose CT or a carbon monoxide diffusing capacity lower than 80% of predicted
  • Age between 55 and 75 years
Not Eligible

You will not qualify if you...

  • Recent history of cancer except non-melanoma skin cancer or carcinoma in situ
  • Other medical conditions posing a significant risk of death

AI-Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Long-term Monitoring

Duration - Up to 20 years or until age 75 or 15 years of smoking abstinence, whichever comes first

Participants undergo annual low-dose CT scans and pulmonary function tests to monitor lung health.

Annual visits for up to 20 years

Trial Site Locations

Total: 2 locations

1

Fundación Jimenez Díaz Universitary Hospital

Madrid, Spain, 28040

Actively Recruiting

2

Pneumology department. Fundación Jimenez Díaz University Hospital

Madrid, Spain, 28040

Actively Recruiting

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Research Team

C

Carolina Gotera, MD

M

María Jesús Rodríguez Nieto, MD phD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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