Actively Recruiting
The Derivation of Human Embryonic Stem Cell Lines From PGD Embryos
Led by Hadassah Medical Organization · Updated on 2025-03-05
70
Participants Needed
1
Research Sites
1390 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Human embryonic stem cells (hESCs) are isolated from the early human embryo and have the capability to proliferate indefinitely in culture and to develop into nearly every cell of the human body. hESC are important for studying developmental biology and for cell replacement therapies for the treatment of degenerative human diseases. An additional use for embryonic stem cells would be for the in vitro study of diseases. hESC lines derived from embryos diagnosed as abnormal by PGD testing would afford such models for study. Because embryos tested by PGD and found to be abnormal would only under rare circumstances be transferred to the uterus of a woman (and in most cases would be discarded), the derivation of new hESC lines from these embryos would provide a viable less ethically-objectionable source of cells with which to study the mechanisms of differentiation and developmental biology.
CONDITIONS
Official Title
The Derivation of Human Embryonic Stem Cell Lines From PGD Embryos
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Couple has derived embryos by IVF.
- Couple has tested these embryos by PGD and does not want to utilize the embryos to build their families.
- Couple signs informed consent.
You will not qualify if you...
- Couple does not sign informed consent.
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Hadassah Medical Organization
Jerusalem, Israel, 91120
Actively Recruiting
Research Team
B
Benjamin E. Reubinoff, M.D. PhD.
CONTACT
S
Shelly E. Tannenbaum, MSQA
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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