Actively Recruiting

Age: 30Years - 75Years
All Genders
NCT05981833

Dermal Allograft Augmentation of Large and Massive Rotator Cuff Tears

Led by Arthrex, Inc. · Updated on 2025-02-24

120

Participants Needed

4

Research Sites

155 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of this study is to compare postoperative healing of large and massive rotator cuff tears with preoperative MRI confirmed fatty infiltration stage II and higher repaired with or without dermal allograft augmentation (DAA).

CONDITIONS

Official Title

Dermal Allograft Augmentation of Large and Massive Rotator Cuff Tears

Who Can Participate

Age: 30Years - 75Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age between 30 and 75 years
  • Planning arthroscopic surgery for full-thickness rotator cuff tear
  • Two complete rotator cuff tears or tear size 3 cm or larger in anterior-posterior or medial-lateral dimension
  • Primary rotator cuff repair
  • Stage II or higher fatty infiltration of supraspinatus or infraspinatus muscle confirmed by preoperative MRI
  • Has dual x-ray absorptiometry or anterior posterior x-ray view of target shoulder
Not Eligible

You will not qualify if you...

  • Unable or unwilling to sign informed consent
  • Objects to use of allograft
  • Stage I or lower fatty infiltration of supraspinatus and infraspinatus muscles
  • Complete full-thickness subscapularis tears greater than superior one third of tendon (Lafosse grade 3+)
  • Glenohumeral joint space less than 2 mm on radiograph
  • Recurrent shoulder instability
  • Corticosteroid injection in operative shoulder within 1 month before surgery
  • Revision rotator cuff repair
  • Preoperative MRI older than 12 months before surgery
  • Pregnant or planning pregnancy during study
  • Workman's compensation case
  • Conditions interfering with study requirements
  • Partial rotator cuff repairs intraoperatively
  • Lafosse grade 3 or higher subscapularis tears intraoperatively

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

University of Arizona, Banner Health

Scottsdale, Arizona, United States, 85006

Actively Recruiting

2

Orthopaedic & Nuerosurgery Specialists

Greenwich, Connecticut, United States, 06831

Actively Recruiting

3

Southern Oregon Orthopedics Research Foundation

Medford, Oregon, United States, 97504

Actively Recruiting

4

Tennessee Orthopedic Foundation for Research Education and Research

Nashville, Tennessee, United States, 37204

Actively Recruiting

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Research Team

C

Caroline Caraci, BA

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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