Actively Recruiting

Phase Not Applicable
Age: 40Years +
All Genders
ID06666790

DermaSensor Postmarket Surveillance Study for Melanoma Detection Using Elastic Scattering Spectroscopy Device

Led by DermaSensor, Inc. · Updated on 2024-10-31

396

Participants Needed

2

Research Sites

21 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to evaluate the sensitivity of the DermaSensor device and investigators in detecting melanoma from suspicious skin lesions. The study focuses on men and women aged 40 and older who have skin lesions that may be melanoma, assessing how well the device and clinical exam can identify concerning lesions. Participants are divided into two groups: one where primary care investigators assess suspicious lesions and decide to biopsy without the device's input, and another where the device's output informs the biopsy decision. The DermaSensor uses elastic scattering spectroscopy, which analyzes light reflected from the lesion to compare it to known benign or malignant patterns. During the study, participants will have their skin lesions examined either with or without the device's assistance. Researchers will measure how sensitive the device is in detecting melanoma over 39 months. Patients will be monitored through the study period to observe the diagnostic process and outcomes, ensuring proper follow-up and safety.

CONDITIONS

Brief Title

DermaSensor Postmarket Surveillance Study

Who Can Participate

Age: 40Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Men or women of any ethnic group aged 40 and older
  • Primary skin lesion suspicious for melanoma
  • Willing and able to read, understand, and sign the informed consent form
Not Eligible

You will not qualify if you...

  • Lesion not accessible to the DermaSensor device handheld unit and tip (e.g., inside ears, under nails)
  • Lesion on areas with psoriasis, eczema, acne, or similar inflammatory skin conditions that prevent device tip placement
  • Lesion larger than 15mm in diameter at widest point
  • Lesion with targeted area less than 2.5mm where device tip cannot be placed entirely within lesion border
  • Lesion with no contiguous area of at least 2.5mm due to ulceration, erosion, or liquid discharge
  • Lesion covered by crust or scale that cannot be cleared to expose at least 2.5mm of intact skin free of crust, ulceration, erosion, or liquid discharge
  • Lesion obstructed by foreign matter that cannot be non-invasively removed (e.g., tattoo, splinter)
  • Lesion not completely cleared of dermoscopy oils, makeup, sunscreen, topical solutions, powders, markings, or staining treatments
  • Lesion located on acral skin such as soles or palms
  • Lesion within 10mm of the eye
  • Lesion on or adjacent to scars, previously biopsied areas, or past surgical intervention sites
  • Lesion located on mucosal surfaces (e.g., genitals, lips)
  • Lesion located in an area with acute sunburn
  • Dementia or neurologic, physical, or psychological limitation preventing consent or follow-up completion

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Surveillance

Duration - Up to 39 months

Participants who undergo routine care are observed while lesions suspicious for melanoma are assessed clinically, with or without the elastic scattering spectroscopy device.

Follow-up visits as part of routine clinical assessment

Trial Site Locations

Total: 2 locations

1

Velocity

New Smyrna Beach, Florida, United States, 32168

Actively Recruiting

2

West Clinical Research

Morehead City, North Carolina, United States, 28557

Actively Recruiting

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Research Team

J

Justin Frazier, MS

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

NON_RANDOMIZED

Model

SEQUENTIAL

Primary Purpose

SCREENING

Number of Arms

2

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