Actively Recruiting

Phase Not Applicable
Age: 18Years +
FEMALE
NCT06483477

Dermatitis During Adjuvant Irradiation for BREAst Cancer:

Led by University Hospital Schleswig-Holstein · Updated on 2025-01-16

268

Participants Needed

5

Research Sites

92 weeks

Total Duration

On this page

Sponsors

U

University Hospital Schleswig-Holstein

Lead Sponsor

U

University of Southern Denmark

Collaborating Sponsor

AI-Summary

What this Trial Is About

In the randomized DAI-BREAC trial, a reminder app will be prospectively tested that reminds breast cancer patients four times each day to perform the required skin care. This will likely contribute to the reduction of grade ≥2 radiation dermatitis in these patients. A total of 268 patients will be randomized to receive standard skin care supported by a reminder app (Arm A) or standard skin care alone (Arm B). Stratification will be done using the three factors treatment volume, radiation boost, and at least one risk factor of dermatitis. Secondary aims include pain (radiation fields), patient satisfaction with the reminder app (Arm A only), impact of the app on the use of health technology (Arm A only), and benefit from support by staff members of the treating Department of Radiation Oncology and/or the UKSH academy regarding the use of the app (Arm A only).

CONDITIONS

Official Title

Dermatitis During Adjuvant Irradiation for BREAst Cancer:

Who Can Participate

Age: 18Years +
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Histologically proven invasive breast cancer
  • Indication for adjuvant hypo-fractionated radiotherapy
  • Possession of and ability to use a smartphone
  • Female gender
  • Age 18 years or older
  • Written informed consent
  • Capacity to provide consent
Not Eligible

You will not qualify if you...

  • Pregnancy or lactation
  • Expected non-compliance

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Trial Site Locations

Total: 5 locations

1

Vejle Hospital, University Hospital of Southern Denmark

Vejle, Southern Denmark, Denmark, 7100

Not Yet Recruiting

2

Medical Practice for Radiotherapy and Radiation Oncology

Hanover, Lower Saxony, Germany, 30161

Not Yet Recruiting

3

Medical School Hamburg, Schwerin Campus

Schwerin, Mecklenburg-Vorpommern, Germany, 19055

Not Yet Recruiting

4

Malteser Hospital St. Franziskus

Flensburg, Schleswig-Holstein, Germany, 24939

Not Yet Recruiting

5

Department of Radiation Oncology, University of Lübeck and University Medical Center Schleswig-Holstein

Lübeck, Germany, 23562

Actively Recruiting

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Research Team

D

Dirk Rades, MD, FASTRO

CONTACT

C

Carlos A. Narvaez-Wolf, MD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

PREVENTION

Number of Arms

2

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Dermatitis During Adjuvant Irradiation for BREAst Cancer: | DecenTrialz