Actively Recruiting

All Genders
NCT05898477

Describing Treatment Outcomes and Responses in Lymphoma-associated Hemophagocytic Lymphohistiocytosis

Led by University of Alabama at Birmingham · Updated on 2026-01-22

2000

Participants Needed

1

Research Sites

269 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The purpose of the study is to describe Hemophagocytic lymphohistiocytosis (HLH) in patients with lymphoma to identify possible therapeutic strategies to improve overall survival of the patients with lymphoma associated hemophagocytic lymphohistiocytosis.

CONDITIONS

Official Title

Describing Treatment Outcomes and Responses in Lymphoma-associated Hemophagocytic Lymphohistiocytosis

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with lymphoma fulfilling at least one of the following:
  • Meeting 5 of 8 HLH-2004 diagnostic criteria
  • Being OHI index positive (sCD25 > 3,900 U/mL and ferritin > 1,000 ng/mL)
Not Eligible

You will not qualify if you...

  • Patients developing HLH more than 1 month after lymphoma diagnosis (for aggressive lymphomas)
  • Patients with incomplete treatment and response documentation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Alabama at Birmingham

Birmingham, Alabama, United States, 35294

Actively Recruiting

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Research Team

G

Gaurav Goyal, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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