Actively Recruiting

Age: 18Years - 40Years
FEMALE
Healthy Volunteers
NCT05473273

Descriptive Analysis of Serum Immunological Markers During an Euploid Frozen Embryo Transfer in a Natural Cycle.

Led by ART Fertility Clinics LLC · Updated on 2025-02-21

40

Participants Needed

1

Research Sites

140 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To describe the peripheral serum levels of the anti-inflammatory cytokines IL-4 (Interleukin-4), IL-10 (Interleukin-10), TGF-ß1 (Transforming Growth Factor beta1), the pro-inflammatory cytokines IL-17 (Interleukin-17), IFγ (Interferon Gamma) and the immune mediator PIBF (Progesterone-Induced Blocking Factor) along a single frozen euploid blastocyst transfer in a natural cycle (NC) or Hormone Replacement Therapy (HRT).

CONDITIONS

Official Title

Descriptive Analysis of Serum Immunological Markers During an Euploid Frozen Embryo Transfer in a Natural Cycle.

Who Can Participate

Age: 18Years - 40Years
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Women aged 18 years to 40 years
  • At least one good quality (grade A or B) chromosomally normal cryopreserved blastocyst available for transfer
  • Undergoing single embryo transfer in a natural cycle or hormone replacement therapy protocol
  • Fertilization performed using fresh ejaculate
Not Eligible

You will not qualify if you...

  • Body mass index below 18.5 or 29 kg/m2 and above
  • Suspected or diagnosed endometriosis or adenomyosis
  • Uterine abnormalities
  • Hydrosalpinx
  • Diagnosed insulin resistance or diabetes mellitus
  • Antiphospholipid syndrome
  • Polycystic ovarian syndrome with at least two Rotterdam criteria
  • History of recurrent miscarriage (loss of 2 or more pregnancies)
  • History of implantation failure after transfer of 2 good-quality euploid embryos
  • History or suspicion of Asherman syndrome
  • Autoimmune disease
  • Couple with first degree consanguinity

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

ART Fertility Clinics LLC

Abu Dhabi, Abu Dhabi Emirate, United Arab Emirates, 60202

Actively Recruiting

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Research Team

B

BARBARA LAWRENZ, PhD

CONTACT

S

SUZAN SAMIR

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Descriptive Analysis of Serum Immunological Markers During an Euploid Frozen Embryo Transfer in a Natural Cycle. | DecenTrialz