Actively Recruiting
Desloratadine in Patients With Ulcerative Colitis
Led by Tanta University · Updated on 2026-01-29
44
Participants Needed
1
Research Sites
57 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of this study is to investigate safety and therapeutic efficacy of antihistamine (desloratadine) on inflammation and disease activity when administered as adjuvant therapies with the traditional therapy 5-aminosalisylic acid (mesalamine) in patients with mild to moderate ulcerative colitis.
CONDITIONS
Official Title
Desloratadine in Patients With Ulcerative Colitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Both male and female sex
- Age between 18 and 65 years
- Active mild to moderate ulcerative colitis as defined by American College of Gastroenterology Clinical Guideline
- Currently treated with 5-aminosalisylic acid (mesalamine)
You will not qualify if you...
- Severe ulcerative colitis
- Significant liver or kidney function abnormalities
- Pregnant or breastfeeding women
- Use of systemic or rectal steroids
- Use of immunosuppressants or biological therapies
- Known allergy to desloratadine or its ingredients
- Presence of other inflammatory diseases
- History of colon cancer
- History of complete or partial colectomy
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Menofia university Hospitals
Shibīn al Kawm, Menofia, Egypt, 32511
Actively Recruiting
Research Team
R
Romisaa R Abd Alnapy
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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