Actively Recruiting
Detecting Clinically Significant Prostate Cancer With Advanced MRI Protocols and Extensive Histopathology
Led by Virdx, Inc. · Updated on 2026-02-25
300
Participants Needed
1
Research Sites
122 weeks
Total Duration
On this page
Sponsors
V
Virdx, Inc.
Lead Sponsor
I
Instituto do Cancer do Estado de São Paulo
Collaborating Sponsor
AI-Summary
What this Trial Is About
In recent years, new and promising approaches have emerged in the field of MRI imaging of the prostate. These approaches usually aim to visualise the so-called "microstructures" of the tissue and are intended to offer greater accuracy in the diagnosis of prostate cancer than the current mpMRI examination. To this end, mathematical microstructure models are calculated that determine the proportional presence of histological substructures in specific MRI volumes. Additional new MRI sequences that are not routinely recorded are required to calculate the microstructure models. In order to further investigate the possibilities of these new MRI sequences, this study will compare different mathematical models. In addition, a histopathological examination of the tissue will be performed.
CONDITIONS
Official Title
Detecting Clinically Significant Prostate Cancer With Advanced MRI Protocols and Extensive Histopathology
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Humans with a prostate 18 years of age or older
- Biopsy-proven prostate cancer patients scheduled for radical prostatectomy
- Signed informed consent confirming understanding of the study purpose and procedures
- Willingness, ability, and legal capacity to participate in the study
- Ability to follow the prohibitions and restrictions defined in the protocol
You will not qualify if you...
- Inability to give consent
- Prior hormone treatment such as androgen deprivation therapy or 5-alpha-reductase inhibitors
- Previous prostate cancer treatment
- Previous transurethral resection of the prostate or other prostate surgery
- Prior total hip replacement or metal implants interfering with MRI of the hip region
- General contraindications for MRI including pacemaker or relevant metal implants
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Instituto do Câncer do Estado de São Paulo
São Paulo, Brazil
Actively Recruiting
Research Team
S
Sina Knapp, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here