Actively Recruiting

Age: 50Years +
All Genders
NCT05955456

Detecting EARLY Heart Failure in Greater Manchester

Led by Manchester University NHS Foundation Trust · Updated on 2025-10-01

600

Participants Needed

1

Research Sites

359 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Heart failure represents a growing public health problem within the UK and particularly within the North West of England. A major challenge is that heart failure is currently diagnosed too late. The researchers have previously developed a risk calculator that accurately identifies individuals at risk of heart failure admission or death before they have developed heart failure. Most risk calculators are never implemented into clinical practice. The researchers will l perform a pilot study to evaluate the risk calculator within primary care in Greater Manchester.

CONDITIONS

Official Title

Detecting EARLY Heart Failure in Greater Manchester

Who Can Participate

Age: 50Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Written informed consent
  • Aged 50 and over
  • Two or more of the following conditions: type 2 diabetes, chronic obstructive pulmonary disease, ischaemic heart disease, atrial fibrillation, hypertension, chronic kidney disease stage 3, body mass index 63 30 kg/m2
Not Eligible

You will not qualify if you...

  • Established diagnosis of heart failure, cardiomyopathy, moderate or severe valvular heart disease, congenital heart disease, or heart transplant
  • Idiopathic, heritable, or drug-induced pulmonary arterial hypertension
  • Any medical condition that increases risk or prevents compliance with study requirements
  • Contraindications to cardiovascular magnetic resonance (CMR) scanning, including pacemaker, defibrillator, intraocular metal, intracranial aneurysm clips, severe claustrophobia
  • Estimated glomerular filtration rate less than 30 ml/min/1.73m2
  • Previous severe allergic reaction or anaphylaxis to gadolinium-based contrast agent
  • Pregnancy or breastfeeding

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Manchester University NHS Foundation Trust

Manchester, Greater Manchester, United Kingdom, m13 9wl

Actively Recruiting

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How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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