Actively Recruiting
Detection of Aneuploidy in Cell Free DNA to Improve the Sensitivity of Diagnostic Peritoneal Lavage in Gastric Cancer
Led by Erasmus Medical Center · Updated on 2025-02-25
63
Participants Needed
1
Research Sites
184 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Aneuploidy may be used as a more sensitive diagnostic tool to detect peritoneal metastasis compared to conventional cytology and imaging techniques. Our aim is to establish whether aneuploidy as detected in cfDNA (as a measure for ctDNA) in PLF of patients with GC may hold value as an additional staging and tumor evaluation method in GC patients.
CONDITIONS
Official Title
Detection of Aneuploidy in Cell Free DNA to Improve the Sensitivity of Diagnostic Peritoneal Lavage in Gastric Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Written informed consent according to ICH-GCP and national/local regulations
- For gastric cancer patients: diagnosed with gastric cancer
- For non-cancer controls: operable patients scheduled for diagnostic laparoscopy for benign conditions such as bariatric or gallbladder disease
You will not qualify if you...
- Language difficulties, dementia, or altered mental status preventing informed consent
- For non-cancer controls: active inflammation or infection
- History of previous malignancies unless completely in remission for at least 5 years, except certain in situ cancers or non-melanoma skin cancers
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Erasmus MC
Rotterdam, Netherlands, 3015GD
Actively Recruiting
Research Team
J
Jessie Huizer, Drs.
CONTACT
N
Niels Guchelaar
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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