Actively Recruiting
Detection and Prediction of Clinically Significant Pneumothorax After Image-guided Transthoracic Lung Biopsy
Led by Chinese University of Hong Kong · Updated on 2025-03-11
330
Participants Needed
1
Research Sites
121 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Objective: The goal of this study is to evaluate the sensitivity and specificity of the presence of pneumothorax on a 4-hour CXR after image-guided transthoracic lung biopsy (TTLB) for diagnosing subsequent clinically significant pneumothorax. Hypothesis to be tested: The investigators hypothesize that an absence of pneumothorax on CXR at 4 hours can accurately predict an absence of clinically significant pneumothorax at 16 to 20 hours. Design and subjects: This is a prospective, single-centre, diagnostic accuracy study conducted at a tertiary referral centre in Hong Kong. Patients will be recruited if an image-guided TTLB is arranged. Study instruments: CXRs will be performed for patients at different time points. The presence and size of pneumothorax (if any) will be recorded. Outcome: The diagnostic capacity of a 4-hour CXR after image-guided TTLB will be provide evidence regarding the safety and patient selection for same-day discharge.
CONDITIONS
Official Title
Detection and Prediction of Clinically Significant Pneumothorax After Image-guided Transthoracic Lung Biopsy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients whose image-guided TTLB, including ultrasound or CT-guided, is arranged for diagnostic purposes
- Patients who are able to sign written informed consent to participate in the study
You will not qualify if you...
- Patients with resolution of lung lesion prior to the scheduled image-guided TTLB
- Patients have active exacerbation of underlying diseases causing unstable respiratory conditions (e.g. exacerbation of COPD, pneumonia) which would lower the threshold for invasive interventions for iatrogenic pneumothorax
- Patients with psychiatric disease or cognitive impairment that may limit their ability to understand or give consent to the study
- Patients who decline to join the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Chinese University of Hong Kong
Hong Kong, Hong Kong
Actively Recruiting
Research Team
K
Ka Pang Chan, MBChB
CONTACT
K
Ka Pang Chan, MBChB
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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