Actively Recruiting

Age: 1Day - 18Years
All Genders
Healthy Volunteers
NCT06406725

Detection of Vocal Fold Motion Impairment on Noninvasive Positive Pressure

Led by Nemours Children's Clinic · Updated on 2026-05-06

50

Participants Needed

1

Research Sites

217 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this prospective, observational study is to evaluate for the presence of vocal fold motion impairment (VFMI) in the children admitted to the pediatric intensive care unit on noninvasive positive pressure ventilation (NIV PPV). Participants will have two ultrasounds of their vocal folds performed, once while on NIV PPV and once after weaned off of the NIV PPV. This results of these scans will be reviewed against one another and against the gold standard, fiberoptic nasolaryngoscopy (FNL). The main question this study aims to answer is: Can POCUS be used to reliably detect VFMI while pediatric patients on supported with NIV PPV?

CONDITIONS

Official Title

Detection of Vocal Fold Motion Impairment on Noninvasive Positive Pressure

Who Can Participate

Age: 1Day - 18Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 0 to 18 years
  • Scheduled to receive a fiberoptic nasolaryngoscopy with the otolaryngology team to assess for vocal fold motion impairment
  • Status post great vessel, esophageal, or tracheal surgery that could disrupt the recurrent laryngeal nerve
Not Eligible

You will not qualify if you...

  • Tracheostomy in place
  • Age over 18 years
  • History of vocal cord paralysis or paresis
  • Cannot have neck in a neutral or slightly extended position due to injury or ligament laxity

AI-Screening

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Trial Site Locations

Total: 1 location

1

Cohen Children's Medical Center

Queens, New York, United States, 11040

Actively Recruiting

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Research Team

A

April Slamowitz, MD

CONTACT

C

Catherine Geller, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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