Laryngeal ultrasound and vocal fold movement in the pediatric cardiovascular intensive care unit.
Julina Ongkasuwan, Elena Ocampo, Brandon Tran
https://pubmed.ncbi.nlm.nih.gov/27107409Actively Recruiting
Led by Nemours Children's Clinic ยท Updated on 2026-05-06
50
Participants Needed
1
Research Sites
8 weeks
Total Duration
This research aims to evaluate vocal fold motion impairment (VFMI) in children admitted to the pediatric intensive care unit who are using noninvasive positive pressure ventilation (NIV PPV). VFMI can result from surgeries affecting the airway, esophagus, or great vessels and may cause voice problems, feeding difficulties, aspiration risk, and airway issues leading to serious health problems. The study investigates whether point-of-care ultrasound (POCUS) can reliably detect VFMI compared to the standard fiberoptic nasolaryngoscopy (FNL), which can be risky in pediatric patients. Participants will undergo two ultrasound scans of their vocal folds: one while on NIV PPV and another after being weaned off it. Between these scans, the usual FNL procedure will be performed by the otolaryngology team to assess the vocal fold motion. This observational study focuses on comparing ultrasound results with FNL findings to determine if POCUS is a safe and effective screening tool for VFMI in this setting. During the study, children will have their vocal folds examined using ultrasound and FNL as part of their care. Researchers will compare these results to measure VFMI presence over a two-year period. The study will monitor the safety and accuracy of ultrasound as a non-invasive method, aiming to reduce the risks associated with FNL. Participants will be followed up to assess outcomes related to vocal fold motion impairment, with the entire process integrated into their clinical treatment timeline.
CONDITIONS
Detection of Vocal Fold Motion Impairment on Noninvasive Positive Pressure
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You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 screening and enrollment visit (in-person)
Duration - Within 1 day
Participants undergo point-of-care ultrasound of the airway while on noninvasive positive pressure ventilation and after removal, alongside standard fiberoptic nasolaryngoscopy (FNL) to assess vocal fold motion impairment.
1 to 2 visits depending on timing of ultrasound and FNL
Duration - Up to 2 years
Participants are observed for outcomes related to vocal fold motion impairment over a period of up to 2 years.
Follow-up visits as per clinical care
Total: 1 location
1
Cohen Children's Medical Center
Queens, New York, United States, 11040
Actively Recruiting
A
April Slamowitz, MD
C
Catherine Geller, MD
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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