Study of High-Intensity Interval Training Effects on Heart Fitness in Adults with Angina and No Obstructive Coronary Artery Disease ANOCA

What this Trial Is About

Researchers are investigating the causes of reduced fitness in patients with Angina and No Obstructive Coronary Artery Disease ANOCA and whether a targeted high-intensity interval training HIIT exercise program can improve their heart function, fitness, and quality of life. The study aims to better understand the link between poor cardiorespiratory fitness and quality of life in these patients by using cardiopulmonary exercise testing CPET to identify exercise limitations and phenotypes. Participants will undergo a 4-week remote HIIT exercise program involving three non-consecutive days per week. The program begins with one supervised treadmill session, followed by remote sessions monitored with Polar heart rate devices and an app. Exercise sessions progressively increase from one-minute intervals to four 4-minute sessions. Participants will wear a wrist-based Polar device daily and a chest strap during exercise to monitor heart rate and adherence. During the study, participants will have baseline and post-exercise CPET assessments to measure peak oxygen consumption and exercise fitness. Questionnaires will assess angina symptoms, cardiac anxiety, functional status, and quality of life. Researchers will track adherence to exercise and evaluate changes in fitness and quality of life after the HIIT program. The study duration for each participant is 4 weeks of intervention with assessments before and after training.

Determinants of Cardiorespiratory Fitness and Effects of HIIT in Patients With ANOCA Obstructive Coronary Artery Disease(ANOCA)