Actively Recruiting
Determinants of the Response to BTK Degraders (BTKd) in Chronic Lymphocytic Leukemia
Led by Nantes University Hospital · Updated on 2026-04-22
60
Participants Needed
14
Research Sites
727 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The aim of the REBELLE cohort - bio-collection is to collect samples from patients with Chronic Lymphocytic Leukemia candidates or those exposed to BTK degraders to evaluate the mechanisms of resistance to these new molecules. To do this, an additional blood or bone marrow sample to those planned in the context of patient care or a residual lymph node biopsy sample will be collected after signing consent.
CONDITIONS
Official Title
Determinants of the Response to BTK Degraders (BTKd) in Chronic Lymphocytic Leukemia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patient with CLL who are candidates for or have been exposed to BTK degraders
- Patient who has provided informed consent to participate in the study
- Patient covered by a social security health insurance plan
You will not qualify if you...
- Minor patients
- Adults under guardianship
- Protected persons
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 14 locations
1
CHU de Angers
Angers, France
Not Yet Recruiting
2
CHU de Bordeaux
Bordeaux, France
Not Yet Recruiting
3
Institut Bergonié
Bordeaux, France
Not Yet Recruiting
4
CHU de Clermont-Ferrand
Clermont-Ferrand, France
Not Yet Recruiting
5
CHD Vendée
La Roche-sur-Yon, France
Not Yet Recruiting
6
Centre Léon Bernard
Lyon, France
Not Yet Recruiting
7
Institut Paoli-Calmettes (Marseille)
Marseille, France
Not Yet Recruiting
8
CHU de Montpellier
Montpellier, France
Not Yet Recruiting
9
CH Régional Universitaire de Nancy
Nancy, France
Not Yet Recruiting
10
University Hospital
Nantes, France
Actively Recruiting
11
Hôpital Avicenne (AP-HP)
Paris, France
Not Yet Recruiting
12
Hôpital Universitaire Pitié Salpêtrière de Paris
Paris, France
Not Yet Recruiting
13
CHU de Poitiers
Poitiers, France
Not Yet Recruiting
14
Centre Henri-Becquerel de Rouen
Rouen, France
Not Yet Recruiting
Research Team
A
ANNE LOK, Dr
CONTACT
B
Benoit Tessoulin, Dr
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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