Study to Find Hidden Heart Failure in At-Risk Adults Aged 40 to 69 in German Cities Using Mobile MRI Screening

What this Trial Is About

Researchers are investigating the prevalence of unrecognized heart failure in adults aged 40 to 69 years who have risk factors but show no symptoms. This observational study focuses on urban populations in large German cities with over 1 million residents, aiming to improve early detection of heart failure and provide a modern screening approach tailored to at-risk patients. The study also compares its findings with a previous trial conducted in rural areas to better understand differences in heart failure prevalence. The study uses a mobile, telemedicine-monitored screening method that includes a non-invasive cardiac magnetic resonance imaging CMR examination without needles, stress, or contrast agents. Participants undergo laboratory tests and quality of life assessments in specially equipped mobile MRI units stationed in major cities. Medical staff operate the mobile units under telemedical supervision, and participant consent is obtained remotely via video calls. Participants will complete questionnaires, blood tests, and the CMR exam at the mobile units. Researchers will track the prevalence of asymptomatic pre-heart failure and chronic kidney disease, as well as adherence to therapy over several years. The study will monitor participants health status at baseline and follow-up points through questionnaires and laboratory data, with the entire participation process occurring in community-based settings to ensure convenience and safety.

Determination of the Prevalence of Unrecognized Heart Failure Among Patients at Risk in Urban Areas Across Germany Using CMR