Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT07048171

TO DETERMINE THE EFFECT OF ALLOGRAFT AND iPRF WITH OR WITHOUT COLLAGEN MEMBRANE ON HEALING OF APICOMARGINAL DEFECTS

Led by Postgraduate Institute of Dental Sciences Rohtak · Updated on 2025-07-02

50

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

To determine the effect of allograft and iPRF with or without collagen membrane on healing of apicomarginal defects : A Randomized Controlled Trial

CONDITIONS

Official Title

TO DETERMINE THE EFFECT OF ALLOGRAFT AND iPRF WITH OR WITHOUT COLLAGEN MEMBRANE ON HEALING OF APICOMARGINAL DEFECTS

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients with no general medical contraindications for oral surgical procedures (ASA-I and ASA-II classification)
  • Patients aged 18 years and above with chronic suppurative apical periodontitis in at least one tooth
  • Radiographic evidence of apical radiolucency with periodontal pocket depth exceeding 6 mm on buccal root aspect
  • Repeated abscess discharge despite satisfactory root canal treatment
  • Presence of apicomarginal defects with denuded buccal bone plate
  • Failed primary root canal treatment
  • Adequate final restoration without clinical evidence of coronal leakage
Not Eligible

You will not qualify if you...

  • Clinical or radiographic evidence of root fracture
  • Resorptive processes involving more than the apical third of the root
  • Chronic generalized periodontitis
  • Failed previous endodontic surgery or failed root canal re-treatment
  • Any systemic disease contraindicating oral surgery, including uncontrolled diabetes and pregnancy
  • Conditions affecting healing rate such as smoking

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

PGIDS

Rohtak, Haryana, India, 124001

Actively Recruiting

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Research Team

D

DR. Sanjay Tewari, MDS

CONTACT

M

Mareesha Mareesha, PG student

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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