Actively Recruiting
Determining Pediatric Usual Hormone Values Using Mass Spectrometry
Led by Assistance Publique - Hôpitaux de Paris · Updated on 2025-08-26
1500
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are conducting a study to establish usual hormone level values in children and adolescents up to 20 years old using liquid chromatography coupled with mass spectrometry (LC-MS/MS). This method allows for precise hormone measurements from small blood samples and aims to improve upon older immunoassay techniques that have limitations and safety concerns. The study is prospective, multicenter, and observational, focusing on healthy individuals without endocrine or acute inflammatory conditions. Participants will have an additional blood sample taken during a routine follow-up blood draw at hospital consultations within the Assistance Publique - Hôpitaux de Paris network. The extra blood volume will be carefully limited based on weight, with a maximum of 2.7 mL collected. The samples will be analyzed by mass spectrometry at specialized clinical metabolomics laboratories under expert supervision. During the study, securely pseudonymized data including age, gender, pubertal stage, and hormone test results will be recorded in a confidential database. Samples and data will be stored securely for up to 15 years following the research phase. The primary goal is to determine normal hormone values in the pediatric population over a one-week measurement period. This research will help improve hormone assay reliability and patient management in clinical practice.
CONDITIONS
Brief Title
Determining Paediatric Usual Values for Hormones Dosages by LC-MS/MS
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Male or female patient 20 years old or younger
- Undergoing a blood sample as part of their routine health follow-up
You will not qualify if you...
- Any identified or suspected endocrine disorder
- Any acute infectious or inflammatory condition
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) during routine health follow-up
Duration - 1 week
Participants undergo an additional blood sample collection during their routine health follow-up to measure hormone dosages using mass spectrometry.
1 visit (in-person) coinciding with routine blood sample collection
Duration - Up to 15 years
Participant samples and data are stored securely for research and reference value establishment over several years.
No additional visits required
Trial Site Locations
Total: 1 location
1
Service d'Endocrinologie Pédiatrique-Explorations Fonctionnelles Hôpital Trousseau
Paris, Paris, France, 75012
Actively Recruiting
Research Team
E
Eloïse Giabicani, MD, PhD
M
Marie-Pierre Luton, PhD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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