Actively Recruiting
Developing Allogeneic Musculoskeletal Therapies
Led by Keele University · Updated on 2025-03-06
325
Participants Needed
1
Research Sites
986 weeks
Total Duration
On this page
Sponsors
K
Keele University
Lead Sponsor
A
Alder Hey Children's NHS Foundation Trust
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this observational study is to analyse the cartilage and bone forming potential of cells isolated from the tissues of patients undergoing surgery for the treatment of polydactyly, hip dislocation and from other bio-banked cartilage tissues. The main question it aims to answer is: Which of the following tissues from polydactyly digit, iliac apophysis or other bio-banked cartilage produce better cartilage in vitro and in vivo? Participants receiving digit amputation surgery for treatment of polydactyly will be asked to donate the associated waste tissue whilst participants receiving surgery to treat a dislocated hip will be asked to donate an extra small piece of cartilage tissue (approximately 1 gram) from the iliac apophysis. Other tissues for the study will be obtained from those donated to biobanks.
CONDITIONS
Official Title
Developing Allogeneic Musculoskeletal Therapies
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Parents or guardians able to provide signed and dated informed consent.
- Scheduled for digit amputation surgery due to polydactyly.
- Scheduled for surgery to treat dislocated hips.
- Informed consent obtained via consenting institution for biobank or NHS Blood and Transplant donors.
You will not qualify if you...
- Parents or guardians do not understand the Patient Information Sheet.
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Robert Jones and Agnes Hunt Orthopaedic and District NHS Trust
Oswestry, Shropshrie, United Kingdom, SY10 7AG
Actively Recruiting
Research Team
K
Karina T Wright, PhD
CONTACT
S
Sharon J Owen, PhD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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