Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
Healthy Volunteers
NCT05109429

Developing a Clinical Outcome Assessment for Opioid Craving

Led by Johns Hopkins University · Updated on 2025-10-23

81

Participants Needed

1

Research Sites

238 weeks

Total Duration

On this page

Sponsors

J

Johns Hopkins University

Lead Sponsor

N

National Institute on Drug Abuse (NIDA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to collect information about opioid craving so that the investigators can develop an opioid craving assessment to improve treatments for individuals with opioid use disorder. To collect this information, the investigators are recruiting individuals in treatment for opioid use disorder who will complete cue-induced opioid craving tasks where these individuals will: (1) look at pictures of neutral objects and touch neutral objects (e.g., water bottles or flashlights), (2) look at opioid-related images, and (3) look and touch opioid-related objects. Participants will then complete a one-on-one interview about the thoughts, feelings and physical sensations the participants experienced during the cue-induced craving session. Participants will also complete questionnaires and existing opioid craving assessments. Finally, participants will provide formal feedback about existing opioid craving assessments with cognitive interviews.

CONDITIONS

Official Title

Developing a Clinical Outcome Assessment for Opioid Craving

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years of age and older
  • Opioid-positive urine sample at admission visit (excluding individuals receiving Naltrexone)
  • Current opioid use disorder diagnosed by DSM-5
  • Currently in treatment for opioid use disorder
Not Eligible

You will not qualify if you...

  • Pregnant, breastfeeding, or may become pregnant during the trial
  • History of psychosis, mania, or other serious psychiatric disorders
  • Suicidal behavior in the past 30 days
  • Circumstances interfering with study participation (e.g., impending jail)
  • Positive for illicit substances other than opioids and cannabis
  • Current substance use disorder other than opioid or nicotine
  • Current intoxication

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Behavioral Pharmacology Research Unit

Baltimore, Maryland, United States, 21224

Actively Recruiting

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Research Team

C

Cecilia L Bergeria, PhD

CONTACT

K

Kelly Dunn, Ph.D., M.B.A.

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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Developing a Clinical Outcome Assessment for Opioid Craving | DecenTrialz