Actively Recruiting

Phase Not Applicable
Age: 25Years - 64Years
FEMALE
NCT06598176

Developing a Combined Molecular Screening and Triage Test for Cervical Cancer in Self-samples

Led by Universiteit Antwerpen · Updated on 2024-09-19

100

Participants Needed

1

Research Sites

674 weeks

Total Duration

On this page

Sponsors

U

Universiteit Antwerpen

Lead Sponsor

U

University Hospital, Antwerp

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of the COMBISCREEN project is to develop a fully molecular cervical screening and triage approach that is applicable on self-samples, which are an easily accessible and non-invasive source of biomarkers. The project allows a one-step screening and triage modality and thereby identifies women with clinically relevant disease that are in need of treatment.

CONDITIONS

Official Title

Developing a Combined Molecular Screening and Triage Test for Cervical Cancer in Self-samples

Who Can Participate

Age: 25Years - 64Years
FEMALE

Eligibility Criteria

Eligible

You may qualify if you...

  • Female
  • 25 until 64 years old
  • Diagnosed with cervical cancer (CIN3+, irrespective of stage) OR in need of conization (irrespective of diagnostic or therapeutic purposes)
  • Has not started any form of cancer treatment prior to study enrollment
  • Written informed consent must be obtained from patient
  • Is able to understand the information brochure and what the study is about
Not Eligible

You will not qualify if you...

  • Women that underwent hysterectomy
  • Pregnant women or 6 weeks post-partum
  • Treatment for cervical (pre)cancer in the last 6 months before participation in the study
  • Participating in another interventional clinical study at the same time
  • Unable to give informed consent
  • Patient has severe anaemia
  • Patient received blood transfusion two weeks before sample collection
  • Blood sampling would compromise patients' overall health
  • Patients who are positive for HIV, Hepatitis B or Hepatitis C
  • Patients who are alcoholic or drug abusers
  • Patients with conditions or abnormalities that might affect study results or patient safety according to investigator judgment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Universitair Ziekenhuis Antwerpen (UZA)

Edegem, Antwerpen, Belgium, 2650

Actively Recruiting

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Research Team

A

Alex Vorsters, Ir, PhD

CONTACT

E

Eef van den Borst, MSc

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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Developing a Combined Molecular Screening and Triage Test for Cervical Cancer in Self-samples | DecenTrialz