Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT05788016

Developing an Opioid Taper Intervention Before Total Joint Arthroplasty

Led by University of Alabama at Birmingham · Updated on 2025-05-29

45

Participants Needed

1

Research Sites

137 weeks

Total Duration

On this page

Sponsors

U

University of Alabama at Birmingham

Lead Sponsor

N

National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The goal of this clinical trial is to develop an pharmacist-led preoperative opioid taper intervention for patients undergoing total knee or hip replacement who are on chronic opioids before their surgery. The main questions it aims to answer are: * Is the intervention feasible and acceptable to patients? * Does the intervention result in a decrease in opioid dose during the preoperative period? Participants will meet with a clinical pharmacist, who will provide some basic education on pain and opioids, and will propose an opioid taper schedule. The pharmacist will then follow-up with the participant by phone each week until surgery to assess progress and adjust the taper as necessary.

CONDITIONS

Official Title

Developing an Opioid Taper Intervention Before Total Joint Arthroplasty

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Decided to pursue primary, unilateral total knee or hip replacement surgery with planned date in 4-8 weeks
  • Currently taking between 20 and 90 milligrams oral opioids daily, with a stable dose for at least 3 months
  • Have a reliable telephone number for contact
  • Speak English
Not Eligible

You will not qualify if you...

  • Taking opioid medications including buprenorphine
  • Taking methadone
  • Taking long-acting opioid pain medications (such as extended-release oxycodone or morphine)
  • Using transdermal opioid medications (such as fentanyl patches)

AI-Screening

AI-Powered Screening

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Trial Site Locations

Total: 1 location

1

UAB Hospital-Highlands

Birmingham, Alabama, United States, 35205

Actively Recruiting

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Research Team

K

Kevin R Riggs, MD

CONTACT

S

Shakristal Williams

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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