Actively Recruiting

Phase Not Applicable
Age: 21Years - 35Years
All Genders
Healthy Volunteers
NCT04907136

Developing and Testing Health Warning Labels on the ENDS Device

Led by Florida International University · Updated on 2026-04-03

80

Participants Needed

1

Research Sites

176 weeks

Total Duration

On this page

Sponsors

F

Florida International University

Lead Sponsor

U

University of Miami

Collaborating Sponsor

AI-Summary

What this Trial Is About

In this project, after systematically developing electronic nicotine delivery systems (ENDS) pictorial health warning labels (HWLs), a proven clinical lab model will be used to examine and test their effect when these are placed on the ENDS device on a variety of subjective (e.g. satisfaction, harm perception, nicotine dependence, intention to quit) and objective outcomes (e.g. plasma nicotine, puff topography) in young adults.

CONDITIONS

Official Title

Developing and Testing Health Warning Labels on the ENDS Device

Who Can Participate

Age: 21Years - 35Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Generally healthy individuals as determined by physical examination
  • Age between 21 and 35 years
  • Willing to provide informed consent
  • Willing to attend lab visits as required by the study
  • Current ENDS users, either daily or occasionally in the past 30 days
  • Have abstained from ENDS use for at least 12 hours prior to each study session
Not Eligible

You will not qualify if you...

  • Regular cigarette smokers (more than 5 cigarettes per month in the past year)
  • Regular users of any other tobacco or nicotine products in the past year
  • Women who are breastfeeding or test positive for pregnancy
  • Individuals with a history of chronic disease or psychiatric conditions
  • Individuals with a history of or active cardiovascular disease, abnormal blood pressure, seizures, or those regularly using prescription medications (other than vitamins or birth control)
  • Use of non-commercial or street e-cigarette liquids or products
  • Current symptoms related to EVALI or COVID-19 such as cough, shortness of breath, chest pain, nausea, vomiting, abdominal pain, diarrhea, fever, chills, or weight loss
  • Exposure to COVID-19 within the last 14 days

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Florida International University

Miami, Florida, United States, 33199

Actively Recruiting

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Research Team

W

Wasim Maziak, MD, PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

CROSSOVER

Primary Purpose

PREVENTION

Number of Arms

2

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