Actively Recruiting

Age: 40Years - 90Years
All Genders
NCT06206369

Developing Trustworthy Artificial Intelligence (AI)-Driven Tools to Predict Vascular Disease Risk and Progression

Led by Amsterdam UMC, location VUmc · Updated on 2024-01-16

11000

Participants Needed

6

Research Sites

287 weeks

Total Duration

On this page

Sponsors

A

Amsterdam UMC, location VUmc

Lead Sponsor

A

Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)

Collaborating Sponsor

AI-Summary

What this Trial Is About

The VASCULAID-RETRO study, within the broader VASCULAID project, aims to create artificial intelligence (AI) algorithms that can predict cardiovascular events and the progression of abdominal aortic aneurysm (AAA) and peripheral arterial disease (PAD). The study plans to gather and analyze data from at least 5000 AAA and 6000 PAD patients, combining existing cohorts and retrospectively collected data. During this project, AI tools will be developed to perform automatic anatomical segmentation and analyses on multimodal imaging. AI prediction algorithms will be developed based on multisource data (imaging, medical history, -omics).

CONDITIONS

Official Title

Developing Trustworthy Artificial Intelligence (AI)-Driven Tools to Predict Vascular Disease Risk and Progression

Who Can Participate

Age: 40Years - 90Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Males and females aged 40 to 90 years with an abdominal aortic aneurysm larger than 3 cm, including infrarenal, juxtarenal, suprarenal, iliac (1.5 times normal diameter), or mycotic aneurysms
  • Patients with AAA who have had interventions or ruptures
  • Males and females aged 40 to 90 years with peripheral arterial disease at any Fontaine stage (1 to 4)
Not Eligible

You will not qualify if you...

  • Patients with aneurysms located in the ascending, thoracic, or thoracoabdominal (type 1-3) regions

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 6 locations

1

Hospital District of Helsinki and Uusimaa (HUS)

Helsinki, Finland

Actively Recruiting

2

Asklepios kliniken hamburg

Hamburg, Germany

Actively Recruiting

3

Amsterdam UMC

Amsterdam, Netherlands

Actively Recruiting

4

University Hospital Center of São João

Porto, Portugal

Actively Recruiting

5

University Clinical Centre of Serbia

Belgrade, Serbia

Actively Recruiting

6

Oxford University Hospitals

Oxford, United Kingdom

Actively Recruiting

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Research Team

K

Kak Khee Yeung, MD, PhD

CONTACT

L

Lotte Rijken, Msc.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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