Actively Recruiting

Age: 18Years +
All Genders
NCT05705219

Development of 3D Multi-Parametric Ultrasound (MPUS) as a Decision Support Tool for Patients

Led by University of California, San Diego · Updated on 2026-01-26

80

Participants Needed

3

Research Sites

264 weeks

Total Duration

On this page

Sponsors

U

University of California, San Diego

Lead Sponsor

N

National Cancer Institute (NCI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

This clinical trial studies how well 3-dimensional multi-parametric ultrasound (3D MPUS) imaging works as a decision-support tool for patients with liver tumors undergoing therapy. Continuous and dynamic imaging of patients undergoing therapy is required to monitor early-phase treatment response.

CONDITIONS

Official Title

Development of 3D Multi-Parametric Ultrasound (MPUS) as a Decision Support Tool for Patients

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Participant has untreated liver metastases from colorectal low-grade adenocarcinoma confirmed by biopsy or imaging and is planning to start a new cancer therapy.
  • Participant is 18 years of age or older.
  • Participant has at least one target lesion measuring 1 cm or more, up to 14 cm, that can be examined by ultrasound.
  • Participant is willing to follow the study protocol.
  • Participant has given written informed consent to join the study.
Not Eligible

You will not qualify if you...

  • Participant has had a severe allergic reaction to ultrasound contrast media or polyethylene glycol (PEG).
  • Participant has medical conditions that would make participation unsafe or impossible, as judged by the treating doctor or study director.
  • Participant is pregnant or breastfeeding.
  • Participant has a cardiac shunt or pulmonary hypertension, which are contraindications for ultrasound contrast agent use.
  • Participant has kidney problems with creatinine levels above 1.5 mg/dl, which is a contraindication for CT imaging.

AI-Screening

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Trial Site Locations

Total: 3 locations

1

Stanford University, School of Medicine

Palo Alto, California, United States, 94305

Actively Recruiting

2

University of California, San Diego

San Diego, California, United States, 92037

Actively Recruiting

3

Thomas Jefferson Hospital

Philadelphia, Pennsylvania, United States, 19107

Actively Recruiting

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Research Team

D

David Marcellus, BS

CONTACT

S

Suzanna Lee

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Development of 3D Multi-Parametric Ultrasound (MPUS) as a Decision Support Tool for Patients | DecenTrialz