Actively Recruiting

FEMALE
Healthy Volunteers
NCT07468201

Development of an Innovative Method to Extract Cord Blood Stem Cells With High Efficiency

Led by Fondazione IRCCS Policlinico San Matteo di Pavia · Updated on 2026-03-12

12

Participants Needed

1

Research Sites

104 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The present study has the purpose to develop an innovative method for obtaining HSCs with a high yield. HSCs extracted from UCB using the traditional method followed by several steps of centrifugation will be compared to the new method which exploit a new biocompatible liquid, capable to separate the HSCs without causing mechanical stress to cells. The potential of ozone treatment to stimulate cells proliferation will be also assessed. Since ozone has been identified as an adjuvant to sustain cytoprotective pathways increasing cell performance, HSCs obtained from UCB samples will be treated by flowing ozone at low concentrations (between 2 and 20 μg/mL) in a mixture 1:1 with oxygen.

CONDITIONS

Official Title

Development of an Innovative Method to Extract Cord Blood Stem Cells With High Efficiency

Who Can Participate

FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Healthy women who have signed the informed consent for umbilical cord donation for research purposes
Not Eligible

You will not qualify if you...

  • Women with inability to comply with the requirements of the protocol
  • Women with viral infections

AI-Screening

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Trial Site Locations

Total: 1 location

1

Fondazione IRCCS Policlinico San Matteo di Pavia

Pavia, Lombardy, Italy, 27100

Actively Recruiting

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Research Team

A

Arsenio Spinillo, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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