Actively Recruiting
Development of IPS from Donated Somatic Cells of Patients with Neurological Diseases
Led by Hadassah Medical Organization · Updated on 2025-03-04
120
Participants Needed
1
Research Sites
1130 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Human fibroblasts and possibly other human somatic cells may be reprogrammed into induced pluripotent stem (iPS) cells by the forced expression of transcription factors (1-5). The iPS cells seem to share many properties with human embryonic stem cells. Induced pluripotent stem cells potentially may be useful in the future as an unlimited source of cells for transplantation. The major goal of the project is to develop human iPS cells from cell cultures from skin biopsies or the patient's hair. The iPS cells will be developed primarily for modeling diseases and drug discovery as well as basic research, and for developing the technology that may eventually allow the use of iPS cells for future transplantation therapy. The iPS cells developed in the course of this application are not intended for use in transplantation therapy. Future development of iPS cells for clinical transplantation therapies will be subjected to the appropriate authorization by ethical and regulatory committees.
CONDITIONS
Official Title
Development of IPS from Donated Somatic Cells of Patients with Neurological Diseases
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Donors with specified neurodegenerative disorders scheduled for surgery or willing to donate intact hairs from the scalp or other body areas
- Healthy donors scheduled for surgery or willing to donate intact hairs from the scalp or other body areas
You will not qualify if you...
- None
AI-Screening
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Trial Site Locations
Total: 1 location
1
Hadassah Ein Kerem
Jerusalem, Israel, Israel, 9112100
Actively Recruiting
Research Team
B
Benjamin E. Reubinoff, MD PhD
CONTACT
S
Shelly E Tannenbaum, MSQA
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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