Long-term Development of IVFICSI Children Born After Frozen Embryo Transfer Using Different Endometrial Preparation Methods

What this Trial Is About

Researchers are studying the long-term development of children born through frozen embryo transfer using different endometrial preparation methods. This study follows up on a previous randomized trial to compare the physical, mental, and motor development of children up to 24 months old. It aims to provide clear information about the safety of the three common preparation protocols natural cycle, modified natural cycle, and artificial cycle in women undergoing frozen embryo transfer. The study involves three groups of children based on the endometrial preparation protocol their mothers underwent natural cycle, modified natural cycle, and artificial cycle. Researchers assess each childs development using tests like the Ages & Stages Questionnaires ASQ-3, which parents help complete. They also examine the childrens physical development and general health and look for any developmental red flags. Participants development is monitored up to 24 months after birth through regular assessments. These include communication, gross motor, fine motor, problem-solving, and personal-social skills measured by the ASQ-3. The study also tracks the rate of children showing developmental concerns from 6 to 24 months. This careful follow-up helps researchers understand the long-term effects of different endometrial preparation protocols on child development.

Development of IVF/ICSI Children Born From Different Endometrial Preparation Protocols