Actively Recruiting

Early Phase 1
Age: 3Days - 15Years
All Genders
ID06267859

Based on Medical Statistical Analysis and Screening (Dispensary) Examination, Identification of the Most Common Somatic and Congenital Diseases in Children, With the Further Development of More Effective Methods of Treatment and Recovery

Led by Tashkent State Medical University (Tashkent Pediatric Medical Institute), Uzbekistan · Updated on 2025-05-21

110

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to clarify the course of common congenital, infectious, and non-infectious diseases in children living in Uzbekistan, focusing on frequently ill children up to age 15. It investigates common congenital diseases, bronchopulmonary and cardiovascular conditions, and evaluates current treatment methods to develop improved therapies and rehabilitation approaches. The study is an early phase 1 clinical trial sponsored by Tashkent State Medical University. The study includes several stages: initially identifying commonly encountered diseases through clinical and laboratory examinations; then assessing effectiveness of standard treatments; followed by developing and applying new treatment tactics approved by an ethics committee. During the rehabilitation phase, microelements and vitamins may be added alongside physiotherapy. The final stage involves creating clinical recommendations for doctors based on research findings. Participants will undergo thorough assessments including medical history collection, physical exams, consultations with specialists, and various laboratory and instrumental tests such as blood and urine analyses, X-rays, ultrasounds, and immunological studies. Quality of life will be evaluated using standardized questionnaires. The study involves long-term monitoring over several years, working with archival data, patient grouping for immunity studies, and clinical trial evaluations to measure outcomes and safety.

CONDITIONS

Brief Title

Development of Methods for Effective Treatment and Improvement of Common Somatic Diseases in Children

Who Can Participate

Age: 3Days - 15Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Children from birth to 15 years old
  • Children permanently residing in the area where the examination is conducted
  • Children included in the group of "frequently ill children"
  • Patients without severe chronic diseases
Not Eligible

You will not qualify if you...

  • Teenagers over 15 years old
  • Patients with severe neurological and mental diseases
  • Patients with endocrinological diseases
  • Patients with long-term chronic somatic diseases
  • Children without genetic pathologies

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Initial Assessment

Duration - Up to 1 year

Participants undergo collection of medical history, clinical and laboratory examinations to identify common diseases among frequently ill children.

Visits as needed for examinations and consultations

Standard Treatment Observation

Duration - Up to 1 year

Participants receive treatment according to approved standards to study its effectiveness.

Visits according to treatment schedule

Experimental Treatment and Rehabilitation

Duration - Up to 3 years

Participants receive the developed treatment tactics including microelements, vitamins, and physiotherapy, to study the effectiveness of new therapy and rehabilitation methods.

Visits according to therapy and rehabilitation schedules

Clinical Recommendations Development

Duration - Up to 5 years

Based on research data, clinical recommendations for doctors are developed.

No additional visits required

Trial Site Locations

Total: 1 location

1

Turdieva Shokhida Tolkunovna

Tashkent, Yunus-obad District, Uzbekistan, 100140

Actively Recruiting

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Research Team

S

Shokhida T Turdieva, DSc

K

Kholida B Abdurashidova

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

5

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