Actively Recruiting
Development of MRI Protocols and Associated Neuro-physiological Explorations in Healthy and Pathological Subjects
Led by University Hospital, Grenoble · Updated on 2023-10-18
600
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are working to develop and improve MRI scanning techniques and related neuro-physiological measurements in both healthy volunteers and patients with various conditions. The goal is to enhance the quality and usefulness of images that assess anatomical, functional, or metabolic brain information, using the latest technology in clinical MRI and other brain exploration equipment. This research is conducted by the University Hospital of Grenoble as part of ongoing efforts to keep their brain imaging tools at the forefront of medical technology. Participants will undergo MRI scans using advanced protocols that may include functional MRI, diffusion tensor imaging, and anatomical imaging. During the MRI sessions, additional devices will monitor eye movements, electrodermal resistance, blood pressure, pulse, breathing, near-infrared spectroscopy for oxygenation measurements, and transcranial electrical stimulation. These procedures aim to optimize imaging sequences and stimulation designs considering the experimental setup and physiological measurements. During the study, participants will be monitored closely while undergoing MRI sessions lasting between one and three hours. Researchers will collect data on brain imaging signals and physiological responses, including eye movement and blood pressure, to evaluate the new protocols. Participants will provide informed consent and be observed for any contraindications or safety concerns. The study includes healthy volunteers and patients, with continuous oversight to ensure data quality and participant safety throughout the research period ending in September 2026.
CONDITIONS
Brief Title
Development of MRI Protocols and Associated Neuro-physiological Explorations in Healthy and Pathological Subjects
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Participants with normal or corrected vision
- Participants affiliated to a social security scheme or beneficiaries of such a scheme
- Participants with French as their mother tongue
- Participants who have given the signed informed consent before carrying out any procedure related to the study
- Volunteer patients will be recruited as part of their follow-up at the CHU. Their pathology will be in agreement with that of the research protocol to be optimized
You will not qualify if you...
- Metallic glitter in the eyes
- Retinal operation
- Claustrophobia
- Wearer of pacemaker, cardiac defibrillator, vascular clip, cardiac prosthesis, insulin pump, implanted medication device, hearing implant, vascular shunt, metal screws, plates, tattoos, piercings, implanted metal objects, or lead shot hunt
- Alcohol ingestion before the examination
- Pregnant, lactating and parturient women
- Major protected by law
- Participants under administrative or judicial supervision
- Participation in another ongoing study if it may interfere with this protocol MAP-IRMaGe
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 1 to 3 hours per session
Participants undergo MRI sessions where various neuro-physiological measurements and imaging protocols are performed to develop and optimize MRI sequences.
1 visit (in-person)
Trial Site Locations
Total: 1 location
1
Unité Mixte de Service IRMaGe US 017
La Tronche, France, 38700
Actively Recruiting
Research Team
A
ATTYE ARNAUD, MD, PhD
C
COUSIN EMILIE, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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