Actively Recruiting

Age: 40Years +
FEMALE
Healthy Volunteers
NCT07148154

Development of a Non-invasive IVD for Endometrial Cancer Screening on High-risk Populations

Led by MiMARK Diagnostics, S.L. · Updated on 2025-08-29

3000

Participants Needed

2

Research Sites

118 weeks

Total Duration

On this page

Sponsors

M

MiMARK Diagnostics, S.L.

Lead Sponsor

H

Hospital Vall d'Hebron

Collaborating Sponsor

AI-Summary

What this Trial Is About

CYTOMARK, a non-invasive in vitro diagnostic (IVD) test measuring a defined panel of protein biomarkers in cervical fluid, can accurately detect endometrial cancer in both symptomatic and asymptomatic women at high risk for the disease. The aim of the study consists in validating CYTOMARK's ELISA test, creating and freezing an algorithm detect EC in post-menopausal women with abnormal uterine bleeding (AUB).

CONDITIONS

Official Title

Development of a Non-invasive IVD for Endometrial Cancer Screening on High-risk Populations

Who Can Participate

Age: 40Years +
FEMALE
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Post-menopausal women (at least 1 year without menstruation) with abnormal uterine bleeding who have either: an endometrium thicker than 3mm by transvaginal ultrasound, OR an endometrium 3mm or less plus at least one of the following: persistent bleeding episodes, heterogeneous endometrium on ultrasound, or risk factors such as BMI of 30 or higher, use of tamoxifen, hormone replacement therapy, Lynch syndrome, or BRCA mutation
  • Ability to provide written informed consent
Not Eligible

You will not qualify if you...

  • Women with an active pelvic infection
  • Women with active or latent viral infections including Hepatitis B, Hepatitis C, or HIV, except those previously treated for Hepatitis C with no viral replication in the last year

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Hospital Universitari de Bellvitge

L'Hospitalet de Llobregat, Barcelona, Spain, 08908

Actively Recruiting

2

Hospital Universitari Campus Vall d'Hebron

Barcelona, Spain, 08035

Actively Recruiting

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Research Team

A

Antonio Gil-Moreno, MD, PhD

CONTACT

E

Eva Colás, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Development of a Non-invasive IVD for Endometrial Cancer Screening on High-risk Populations | DecenTrialz