Actively Recruiting

Age: 18Years - 90Years
All Genders
Healthy Volunteers
NCT06078930

Development of Novel Gastric Cancer Screening and Diagnosis Technologies Using Tongue Imaging and Study of Tongue Image Changes Mechanisms

Led by Zhejiang Cancer Hospital · Updated on 2025-06-04

100000

Participants Needed

1

Research Sites

291 weeks

Total Duration

On this page

Sponsors

Z

Zhejiang Cancer Hospital

Lead Sponsor

S

Sichuan Cancer Hospital and Research Institute

Collaborating Sponsor

AI-Summary

What this Trial Is About

In this study, the investigators will prospectively recruit 100,000 individuals, including gastric cancer patients who have not undergone any anti-tumor treatment and non-gastric cancer participants. The investigators will construct a diagnostic model for malignant tumors based on the combination of tongue imaging, tongue coating, saliva, gastric juice, and fecal multi-omics data (including metagenomics, proteomics, metabolomics, etc.). Additionally, the study will explore the relationship between oral, gastric, and intestinal microbiota and the development of malignant tumors.

CONDITIONS

Official Title

Development of Novel Gastric Cancer Screening and Diagnosis Technologies Using Tongue Imaging and Study of Tongue Image Changes Mechanisms

Who Can Participate

Age: 18Years - 90Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Aged between 18 and 90 years
  • Histologically or cytologically confirmed gastric cancer (for patients)
  • No prior chemotherapy, radiotherapy, biotherapy, immunotherapy, or other anti-tumor treatment for gastric cancer (for patients)
  • Willingness to participate, sign informed consent, and ability to comply with follow-up (for all participants)
  • Healthy participants aged between 18 and 90 years
Not Eligible

You will not qualify if you...

  • Having two or more types of malignant tumors at the same time (for patients)
  • Prior treatment of gastric cancer with chemotherapy, radiotherapy, biotherapy, immunotherapy, or other anti-tumor therapy (for patients)
  • Use of glucocorticoids or antibiotics within the past three months (for all participants)
  • History of long-term medication (for all participants)
  • Presence of oral diseases such as tooth and gum diseases (for all participants)
  • Development of severe diseases, including mental illness, that require combined treatment or affect safety or data collection
  • Seriously abnormal laboratory examination values
  • Family or social factors that might affect safety or data collection, as judged by researchers

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Zhejiang Cancer Hospital

Hangzhou, Zhejiang, China, 310022

Actively Recruiting

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Research Team

X

Xiangdong Cheng, MD

CONTACT

Z

Zhiyuan Xu, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Development of Novel Gastric Cancer Screening and Diagnosis Technologies Using Tongue Imaging and Study of Tongue Image Changes Mechanisms | DecenTrialz