Actively Recruiting
Development of Novel Imaging and Molecular Biomarkers of Fibrosis in Patient With Ulcerative Colitis
Led by IRCCS San Raffaele · Updated on 2026-01-15
50
Participants Needed
1
Research Sites
88 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Prospective multicenter interventional non-randomized cross-sectional study. Ultrasound operators will be blinded to clinical and endoscopic findings and the endoscopist will be blinded of the clinical and ultrasound findings. This study aims to develop novel imaging and molecular biomarkers of fibrosis, through the use of intestinal ultrasound and shear wave elastography, using histologic specimens obtained by endoscopic biopsies as reference standard.
CONDITIONS
Official Title
Development of Novel Imaging and Molecular Biomarkers of Fibrosis in Patient With Ulcerative Colitis
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adult, 18 years of age and older
- Established diagnosis (> three months) of ulcerative colitis
- Scheduled to undergo colonoscopy according to current standards of care and ECCO guidelines
- Ability to understand and comply with the study procedures and sign an informed consent form
You will not qualify if you...
- Pregnancy
- Presence of ascites, active infections, or any contraindication to colonoscopy (e.g., intolerance to preparation, severe flare)
- Inability to undergo intestinal ultrasound within the time set by the study
- Poor quality of ultrasound imaging due to luminal gas or body habitus
- Diagnosis of malignancy in the pathological specimen
- Need to change therapy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
IRCCS San Raffaele Hospital, Milano
Milan, Lombardy, Italy, 20132
Actively Recruiting
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
OTHER
Number of Arms
1
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