Actively Recruiting
Development of Optimal Sensory Feedback Strategies to Maximize Function After Tetraplegia
Led by Case Western Reserve University · Updated on 2026-02-19
3
Participants Needed
1
Research Sites
241 weeks
Total Duration
On this page
Sponsors
C
Case Western Reserve University
Lead Sponsor
U
University Hospitals Cleveland Medical Center
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this clinical trial is to learn more about how stimulating the nerves involved in sensation (either in the limbs or in the brain) can be used to restore sensation in participants who have a spinal cord injury. Participants in this study will have already been enrolled in the "Reconnecting the Hand and Arm to the Brain (ReHAB)" study, and received small electrodes in a part of the brain that is involved in sensing touch and pressure in the hand. The ReHAB study participants will also have received electrodes around the nerves in their arm. In this clinical trial, participants will receive two types of electrical stimulation: * Intracortical microstimulation (ICMS) which involves sending small electrical pulses to the part of the brain that processes sensation. * Peripheral nerve stimulation (PNS) which involves sending small electrical pulses to the nerves in the arm that transmit sensations from the hand. Researchers will try different patterns of stimulation for both ICMS and PNS and study how the participants perceive the sensations from the different stimulation patterns. The researchers will also study how combining ICMS and PNS affects the perceived sensations.
CONDITIONS
Official Title
Development of Optimal Sensory Feedback Strategies to Maximize Function After Tetraplegia
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Enrolled in the ReHAB clinical trial and received ReHAB system components via implantation surgery
- Willingness and availability to follow the study protocol
You will not qualify if you...
- Lack of function or operability of all implanted ReHAB system components
- Severe pain or other chronic medical condition that would prevent the participant from completing study-related activities
AI-Screening
AI-Powered Screening
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Trial Site Locations
Total: 1 location
1
Case Western Reserve University
Cleveland, Ohio, United States, 44106
Actively Recruiting
Research Team
E
Emily Graczyk, Ph.D.
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DEVICE_FEASIBILITY
Number of Arms
1
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