Actively Recruiting
Development of a Prediction Model for Delirium After Cardiac Surgery Using a Novel Self-Administered Preoperative Cognitive Assessment Tool
Led by University Hospital, Basel, Switzerland · Updated on 2025-01-27
475
Participants Needed
1
Research Sites
17 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This research focuses on elderly patients undergoing cardiac surgery who are at increased risk of postoperative delirium (POD) and postoperative cognitive dysfunction (POCD), conditions linked to higher illness and death rates. The study aims to validate a self-administered cognitive assessment tool called CogCheck to predict the risk of POD in this group, addressing the challenge that cognitive impairment often goes undiagnosed before surgery due to time and personnel constraints. Previous risk prediction models for delirium after cardiac surgery have limitations, making this validation important for better identifying high-risk patients. Participants will use the CogCheck application, a tablet-based program developed to assess cognitive function efficiently and independently. Data will be collected from patients undergoing elective cardiac surgery, focusing on their performance within the app. The study compares patients who develop delirium after surgery with those who do not to determine which parts of the CogCheck assessment best predict POD. This observational study does not involve experimental treatments but monitors cognitive performance related to surgery. Participants will be monitored for postoperative delirium three times daily from the first day after surgery until discharge from intensive or intermediate care, for up to 50 days. The study collects detailed cognitive assessment data before surgery using the CogCheck tool, alongside medical and surgical information. Researchers will create risk profiles based on these assessments to help target preventive strategies for those at higher risk. The total duration of involvement spans from preoperative assessment through postoperative monitoring until hospital discharge or up to 50 days post-surgery.
CONDITIONS
Brief Title
Development of a Prediction Model for Delirium After Cardiac Surgery Using a Novel Self-Administered Preoperative Cognitive Assessment Tool
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Elective cardiac surgery
- Age 60 years or older
- Good knowledge of the German language
- Written informed consent
You will not qualify if you...
- Emergency surgery
- Medical instability limiting preoperative assessment
- Surgical procedures without cardiopulmonary bypass
- Procedures involving deep hypothermic circulatory arrest
- Concurrent carotid surgical procedures
- Participation in an interventional trial with postoperative delirium or cognitive dysfunction as primary endpoint
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 1 day before surgery
Participants complete the self-administered CogCheck cognitive assessment before cardiac surgery to evaluate their risk for postoperative delirium.
1 visit (in-person)
Duration - Up to 50 days post-surgery
Participants are monitored for postoperative delirium three times daily from postoperative day 1 until discharge from the ICU or IMC.
Multiple daily assessments during ICU or IMC stay
Trial Site Locations
Total: 1 location
1
University Hospital Basel
Basel, Switzerland, 4031
Actively Recruiting
Research Team
N
Nicolai Goettel, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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