Actively Recruiting
Development of Prosocial Behaviors and Related Brain Network in Infants of High and Low Risk of ASD
Led by Children's Hospital of Fudan University · Updated on 2026-03-16
100
Participants Needed
1
Research Sites
273 weeks
Total Duration
On this page
Sponsors
C
Children's Hospital of Fudan University
Lead Sponsor
S
ShanghaiTech University
Collaborating Sponsor
AI-Summary
What this Trial Is About
The goal of this observational study is to compare the developmental trajectories of prosocial behaviors and functional network connections in infants and toddlers at high and low risk of autism spectrum disorder (ASD). The main questions it aims to answer are what the differences in prosocial behaviors and related brain network connections between infants/toddlers at high and low risk of ASD are. Participants will receive developmental and social communicational assessments (Griffiths Mental Developmental Scales, Peabody Developmental Motor Scales, The Communication and Symbolic Behavior Scales Developmental Profile Infant-Toddler Checklist), resting-state EEG and MRI in a natural sleeping state.
CONDITIONS
Official Title
Development of Prosocial Behaviors and Related Brain Network in Infants of High and Low Risk of ASD
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Subjects are enrolled as high-risk if they have an older sibling with a confirmed clinical diagnosis of ASD by ADOS-2 or ADI-R
- Subjects are enrolled in the low-risk group if they have an older sibling without ASD and no family history of ASD in first or second-degree relatives
You will not qualify if you...
- Diagnosis or physical signs strongly suggesting genetic conditions or syndromes linked to ASD (e.g., fragile X syndrome)
- Significant medical or neurological conditions affecting growth, development, or cognition (e.g., CNS infection, seizure disorder, congenital heart disease)
- Sensory impairments such as vision or hearing loss
- Low birth weight (less than 2000 grams) or prematurity (less than 37 weeks gestation)
- Possible brain injury from prenatal exposure to harmful substances (e.g., alcohol, certain medications)
- Contraindications for MRI, such as metal implants
- Family history of intellectual disability, psychosis, schizophrenia, or bipolar disorder in a first-degree relative
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Children's Hospital of Fudan University
Shanghai, China
Actively Recruiting
Research Team
B
Bingrui Zhou, doctor
CONTACT
C
Chunchun Hu, master
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here