Actively Recruiting

Phase Not Applicable
Age: 18Years - 75Years
All Genders
Healthy Volunteers
NCT07270601

Development of a Quantifiable Ultrasound Biomarker for Hepatic Steatosis

Led by ContextVision AB · Updated on 2025-12-08

110

Participants Needed

1

Research Sites

58 weeks

Total Duration

On this page

Sponsors

C

ContextVision AB

Lead Sponsor

U

University of Washington

Collaborating Sponsor

AI-Summary

What this Trial Is About

The research study is considering a non-invasive way to measure the percentage of fat in the liver using ultrasound. This could help detect early signs of a very common condition called metabolic dysfunction-associated steatotic liver disease (MASLD). Current tests, like MRI or biopsy, can be expensive or invasive. If successful, this ultrasound tool could become an easier and more accessible way to monitor liver health - especially for people with obesity, diabetes, high blood pressure, or high cholesterol.

CONDITIONS

Official Title

Development of a Quantifiable Ultrasound Biomarker for Hepatic Steatosis

Who Can Participate

Age: 18Years - 75Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients aged 18 to 75 years
  • Willingness and ability to provide consent to participate in the study
  • Diagnosed or suspected MASLD from a hepatology clinic OR belonging to a high-risk group with diabetes, obesity (BMI ≥ 25 kg/m²), high cholesterol, or high blood pressure
  • Healthy volunteers aged 18 to 75 years with no suspicion of MASLD based on lab, imaging, or clinical exams
  • Healthy volunteers without known metabolic conditions such as metabolic syndrome, diabetes, obesity, insulin resistance, or dyslipidemia
Not Eligible

You will not qualify if you...

  • Pregnancy or nursing
  • Contraindications to MRI such as severe claustrophobia, pacemaker, or metallic/mechanical implants
  • Acute illness or cognitive impairment preventing cooperation with MRI and ultrasound breath-holding instructions
  • Body mass index (BMI) greater than 35 kg/m²
  • History of excessive alcohol consumption or drug use within the past 2 years
  • Known acute or chronic hepatitis or other liver diseases
  • Presence of congenital liver anomalies
  • Known cirrhosis
  • Known active cancer

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Washington

Seattle, Washington, United States, 98195

Actively Recruiting

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Research Team

L

Laura Sissons-Ross Research Manager

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

DIAGNOSTIC

Number of Arms

1

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