Actively Recruiting
Development of Radiation Free Whole Body Magnetic Resonance (MR) Imaging Technique for Staging Children With Cancer
Led by Heike E Daldrup-Link · Updated on 2024-11-25
75
Participants Needed
1
Research Sites
773 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
A research study on the diagnosis of spread of disease for children who have been diagnosed with solid tumors using a new whole body imaging technique and a new MR contrast agent (ferumoxytol). Standard tests that are used to determine the extent and possible spread of a child's disease include magnetic resonance (MR) imaging, computed tomography (CT), Positron Emission Tomography (PET) as well as bone scanning, and metaiodobenzylguanidine (MIBG) scanning. The purpose of this study is to determine if newer imaging tests referred to as whole body diffusion-weighted MR and whole body PET/MR can detect the extent and spread of the disease as accurately or even better as the standard tests (CT, MR and/or PET/CT). The advantage of the new imaging test is that it is associated with no or significantly reduced radiation exposure compared to standard CT and PET/CT imaging tests. The results of whole body MR and PET/MR will be compared with that of the conventional, standard imaging studies for tumor detecting.
CONDITIONS
Official Title
Development of Radiation Free Whole Body Magnetic Resonance (MR) Imaging Technique for Staging Children With Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of a solid extra-cranial tumor like malignant lymphoma or malignant sarcoma
- Scheduled for or completed a 18F-FDG-PET or 18F-FDG-PET/CT tumor staging procedure
- No restrictions on prior treatment
- Participant or parent/guardian consented, with assent from minors as appropriate
You will not qualify if you...
- MR-incompatible metal implants
- Need for sedation or claustrophobia
- Hemosiderosis or hemochromatosis (except for inclusion in a study branch without ferumoxytol)
- Iron overload preventing use of ferumoxytol
- History of allergic reactions to iron compounds or severe allergies
- Pregnant women and fetuses
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Stanford University Cancer Institute
Stanford, California, United States, 94305
Actively Recruiting
Research Team
L
Lucia Barrato
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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