Actively Recruiting
Development of a Swiss Surveillance Database for Molecular Epidemiology of Hypervirulent and Multi-drug Resistant Pathogens
Led by University Hospital, Basel, Switzerland · Updated on 2025-05-14
10000
Participants Needed
5
Research Sites
535 weeks
Total Duration
On this page
Sponsors
U
University Hospital, Basel, Switzerland
Lead Sponsor
S
Swiss National Science Foundation
Collaborating Sponsor
AI-Summary
What this Trial Is About
Hypervirulent and multidrug-resistant infections are associated with significant health care costs, substantial morbidity and mortality. Therefore, the rapid recognition of outbreaks and transmissions with hypervirulent and multi-drug resistant pathogen is a key priority for infection control and public health.The main goal is to implement a shared database, connecting human and veterinary microbiology laboratories, which would allow near real-time molecular epidemiology with high spatiotemporal resolution of bacterial pathogens such as transmission and outbreak surveillance between different compartments including humans, animals and the environment in Switzerland. Investigator aims to analyze already collected encoded retrospective datasets of various pathogens by combining epidemiological data and whole genome sequences from pathogens.
CONDITIONS
Official Title
Development of a Swiss Surveillance Database for Molecular Epidemiology of Hypervirulent and Multi-drug Resistant Pathogens
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients with colonization or infection by bacterial or viral pathogens with available whole genome sequencing data
- Availability of minimal epidemiological, demographic, and clinical data for the patient
- Pathogens included: multidrug-resistant bacteria (e.g., MRSA, ESBL-producing Enterobacteriaceae, Pseudomonas aeruginosa, Acinetobacter baumannii, Vancomycin resistant Enterococcus faecium), virulent bacteria (e.g., Neisseria meningitidis, Neisseria gonorrhoeae, Mycobacterium tuberculosis, Campylobacter, Salmonella, Legionella pneumophila, Listeria monocytogenes, Streptococcus pneumoniae), and viruses (e.g., Influenza viruses, Measles virus, Enterovirus E68, Respiratory Syncytial Virus)
You will not qualify if you...
- Decline to sign general consent or any other statement refusing use of data for research purposes
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 5 locations
1
University Hospital Basel
Basel, Switzerland, 4031
Actively Recruiting
2
University of Bern
Bern, Switzerland, 3012
Actively Recruiting
3
University Hospital Geneva
Geneva, Switzerland, 1205
Actively Recruiting
4
University Hospital Lausanne CHUV
Lausanne, Switzerland, 1011
Actively Recruiting
5
University of Zurich
Zurich, Switzerland, 8057
Actively Recruiting
Research Team
H
Hans Hirsch, Prof. Dr.
CONTACT
A
Aitana Lebrand, Dr.
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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