Actively Recruiting
Led by Indian Council of Medical Research · Updated on 2025-08-14
1650
Participants Needed
2
Research Sites
30 weeks
Total Duration
I
Indian Council of Medical Research
Lead Sponsor
S
St Johns Medical College Hospital, Bangalore, India
Collaborating Sponsor
Researchers are evaluating whether a deprescribing tool can help reduce prescriptions with potentially inappropriate medications (PIMs) among elderly patients in India. The study aims to determine if inappropriate polypharmacy can be lowered by developing and implementing a tool tailored to the Indian context, where medication use patterns differ from other countries. This trial compares outcomes between physicians who use the deprescribing tool and those who follow routine prescribing practices. In this multicenter study, physicians are randomly assigned to either a control group that prescribes as usual or an intervention group that uses the deprescribing tool during patient consultations. The tool guides medication review and deprescribing decisions, such as stopping duplicate drugs, tapering unnecessary medications, or reducing doses. Patients aged 60 years and older receive routine care from their assigned physician, and prescriptions are collected for evaluation. Participants are followed for one month after the consultation to monitor adverse events, including hospitalizations. Data collected include the proportion of prescriptions containing PIMs, average number of PIMs per prescription, deprescribing rates, and potential adverse drug reactions or interactions. Researchers assess the impact of the tool on improving prescription quality and reducing medication-related risks, with the total participation lasting from enrollment through follow-up.
CONDITIONS
Development, Validation and Evaluation of a Deprescribing Tool
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 30 minutes to 1 hour
Participants receive medication review using the deprescribing tool during their consultation, where prescribers may deprescribe medications if indicated.
1 visit (in-person)
Duration - 1 month
Participants are followed up approximately one month after consultation to monitor for any adverse events, including hospitalizations, via telephone or in person if a routine follow-up visit occurs.
1 follow-up visit (telephone or in-person)
Total: 2 locations
1
St. John's Medical College, Bangalore, India
Bangalore, Karnataka, India, 560034
Actively Recruiting
2
All India Institute of Medical Sciences Bhopal
Bhopal, Madhya Pradesh, India, 462020
Actively Recruiting
R
Ratinder Jhaj, DM
D
Dr. Atiya Faruqui, MD
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
SEQUENTIAL
Primary Purpose
OTHER
Number of Arms
2
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