Creating and Testing a Risk Model for Gastric Retention in Adults Undergoing Sedated Gastroscopy Procedures

What this Trial Is About

Researchers are evaluating gastric retention in patients undergoing sedated gastroscopy to improve safety and examination quality. This observational study aims to develop and validate a standardized gastric residual volume GRV grading system to measure the volume of retained stomach contents. It also investigates how demographic factors, comorbidities, and medication history affect gastric emptying. The goal is to create a simple, endoscopy-based assessment tool for gastric retention risk. The study involves two groups a model development cohort of 3,000 patients to identify risk factors and build a prediction model, and an external validation cohort of 2,000 patients from multiple centers to test the models accuracy. Patients scheduled for elective sedated gastroscopy or sedated gastro-colonoscopy will be included. There is no intervention instead, participants undergo routine endoscopic examination during which gastric residual volume is graded. Participants will be followed during their hospital stay, typically about 2 hours, while researchers measure delayed gastric emptying using the GRV grading system. Secondary measures include correlation of GRV with symptom scores and development of a simplified risk scoring system. Data collection focuses on patient demographics, comorbidities, medications, and gastroscopy findings. Safety and outcome data are recorded during this short observation period.

Development and Validation of a Risk Prediction Model for Gastric Retention in Patients Undergoing Sedated Gastroscopy