Actively Recruiting

Age: 18Years +
All Genders
NCT07104214

Development and Validation of a Risk Prediction Model for Gastric Retention in Patients Undergoing Sedated Gastroscopy

Led by Zhejiang University · Updated on 2026-03-11

5000

Participants Needed

3

Research Sites

43 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Gastric retention not only compromises the quality of endoscopic examination but also significantly increases the risk of reflux and aspiration in sedated patients. Aspiration of gastric contents represents a critical anesthesia-related complication during the perioperative period, carrying substantial implications for anesthetic management. With the growing volume of sedated gastroscopy procedures, predicting gastric retention has become an urgent clinical priority. This prospective study aims to establish a standardized gastric residual volume (GRV) grading system to evaluate both the volume of retained gastric contents and its contributing factors in patients undergoing upper gastrointestinal endoscopy. We will systematically assess the impact of demographic characteristics, comorbidities, and medication history on gastric emptying function. This study will facilitate establishment of an endoscopy-based simplified assessment system for gastric retention.

CONDITIONS

Official Title

Development and Validation of a Risk Prediction Model for Gastric Retention in Patients Undergoing Sedated Gastroscopy

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 18 years or older
  • Scheduled for elective sedated gastroscopy or sedated gastro-colonoscopy
  • Provided informed consent to participate
Not Eligible

You will not qualify if you...

  • Acute upper gastrointestinal bleeding (active hematemesis, melena, or confirmed bleeding within 24 hours)
  • Emergency endoscopic procedures
  • Known pregnancy or lactation
  • Deemed ineligible by the investigators

AI-Screening

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Trial Site Locations

Total: 3 locations

1

The First Affiliated Hospital, Zhejiang University School of Medicine

Hangzhou, Zhejiang, China, 310000

Actively Recruiting

2

The Second Affiliated Hospital of Jiaxing University

Jiaxing, Zhejiang, China, 314000

Actively Recruiting

3

The Fifth Affiliated Hospital of Wenzhou Medical University

Lishui, Zhejiang, China, 323000

Not Yet Recruiting

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Research Team

D

Diansan Su, Chief Physician

CONTACT

M

Mingxia Xu

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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