Actively Recruiting

All Genders
NCT06380192

Developmental and Epileptic Encephalopathy of Genetic Etiology: Natural History Through Reuse of Clinical Data

Led by Imagine Institute · Updated on 2025-06-29

400

Participants Needed

23

Research Sites

113 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Developmental and Epileptic Encephalopathy (DEE) are a heterogeneous group of neurodevelopmental disorders linked to both epilepsy and its underlying etiology, independently of epileptiform activity. The creation of a database with retrospective follow-up of a large number of patients on a national scale will enable better knowledge of specific biomarkers, and thus a better classification and understanding of the natural evolution of DEE according to their etiology. This will enable better, more personalized therapeutic management of patients, depending on etiology and the presence or absence of these biomarkers. The investigators will also be able to draw up management recommendations, which are currently non-existent.

CONDITIONS

Official Title

Developmental and Epileptic Encephalopathy of Genetic Etiology: Natural History Through Reuse of Clinical Data

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of Developmental and Epileptic Encephalopathy
  • Registered with or benefiting from a social security scheme.
Not Eligible

You will not qualify if you...

  • Opposition of the patient or his/her parents to the re-use of data in the context of this study
  • Person subject to a safeguard of justice measure

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 23 locations

1

CHU Amiens

Amiens, France

Not Yet Recruiting

2

CH Angers

Angers, France

Not Yet Recruiting

3

Chu Besancon

Besançon, France

Not Yet Recruiting

4

CHU Bordeaux

Bordeaux, France

Not Yet Recruiting

5

CHRU Brest

Brest, France

Not Yet Recruiting

6

CHU Clermont-Ferrand

Clermont-Ferrand, France

Not Yet Recruiting

7

CHU Grenoble

Grenoble, France

Not Yet Recruiting

8

CHU Lille

Lille, France

Not Yet Recruiting

9

CHU Limoges

Limoges, France

Not Yet Recruiting

10

CHU Lyon HCL

Lyon, France

Not Yet Recruiting

11

Assistance Publique Hopitaux de Marseille

Marseille, France

Not Yet Recruiting

12

CHU de Nancy

Nancy, France

Not Yet Recruiting

13

Hopitaux Pediatriques de Nice CHU Lenval

Nice, France

Not Yet Recruiting

14

Necker-Enfants Malades Hospital

Paris, France, 75015

Actively Recruiting

15

CHU Pitié Salpétrière

Paris, France

Not Yet Recruiting

16

CHU Robert Debré

Paris, France

Not Yet Recruiting

17

Hôpital Armand Trousseau

Paris, France

Not Yet Recruiting

18

Chu Reims

Reims, France

Not Yet Recruiting

19

CHU Rennes

Rennes, France

Not Yet Recruiting

20

CHU Strasbourg

Strasbourg, France

Not Yet Recruiting

21

CHU Toulouse

Toulouse, France

Not Yet Recruiting

22

CHRU Tours

Tours, France

Not Yet Recruiting

23

Hôpital André Mignot (CH Versailles)

Versailles, France

Not Yet Recruiting

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Research Team

R

Rima Nabbout, Pr

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Developmental and Epileptic Encephalopathy of Genetic Etiology: Natural History Through Reuse of Clinical Data | DecenTrialz