Actively Recruiting

Age: 50Years +
All Genders
ID05206981

IlluminOss Device Global Registry A Prospective, Post-Market, Multi-Center Evaluation of Clinical Outcomes

Led by IlluminOss Medical, Inc. · Updated on 2026-04-17

300

Participants Needed

16

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are gathering information on the IlluminOss Device, which is used to stabilize and align bones in patients with traumatic or pathological fractures. This multi-center, observational patient registry aims to collect safety and performance data on this device as part of standard medical care. The study includes patients aged 50 and older who are candidates for the device. Patients who have received or will receive the IlluminOss Device are included in the registry. Data collection starts at the initial clinic visit and includes both prospective and retrospective entries. Medical details, surgical information, hospital discharge data, and any adverse events are recorded. Participants will complete patient-reported surveys such as PROMIS physical function, Visual Analog Pain Score (VAS), and Veterans Rand 12 (VR 12) before surgery and at 75 days, 6 months, and 12 months after the procedure. Throughout the study, patients will undergo scheduled clinical and radiographic evaluations to monitor outcomes. Researchers will track safety success rates, complications, device implantation success, fracture healing, disability, return to work status, discharge status, and patient-reported outcomes over 12 months. The study is designed to observe real-world use of the device and its effects on patient recovery and function over time.

CONDITIONS

Brief Title

Device Global Registry for the IlluminOss Bone Stabilization System

Who Can Participate

Age: 50Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient has been deemed a candidate for the IlluminOss device
  • Patient is male or non-pregnant female
  • Patient is willing and able to comply with the postoperative scheduled clinical and radiographic evaluations
  • Patient is willing and able to give informed consent if required
  • Traumatic patient is over the age of 50
  • IlluminOss procedure is the initial procedure to treat the traumatic injury
Not Eligible

You will not qualify if you...

  • Active or incompletely treated infection at the implant site (U.S. and EU)
  • Allergy to implant materials or dental glue (U.S. and EU)
  • Intramedullary canal smaller than delivery sheath diameter at fracture site (U.S. and EU)
  • Distant infections that may spread to implant site (U.S. and EU)
  • Open fractures with severe contamination (U.S. and EU)
  • Delivery sheath unable to cross fracture site after proper reduction and realignment (U.S. and EU)
  • Skeletally immature patients (EU)
  • Uncooperative or neurologically impaired patients unable to follow directions (EU)
  • Vascular insufficiency (EU)
  • Extremely comminuted fractures with insufficient balloon holding power (EU)
  • Patients under 50 years old for acute humerus fractures (EU)
  • Metabolic disorders impairing bone formation excluding pathologic humerus (EU)
  • Osteomalacia excluding pathologic humerus (EU)
  • Muscular atrophy or neuromuscular disease excluding pathologic humerus (EU)

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Implementation

Duration - Single procedure

Participants undergo implantation of the IlluminOss bone stabilization device as part of their routine clinical care.

1 visit (in-person)

Post-operative Follow-up

Duration - 12 months

Participants complete questionnaires and clinical assessments to monitor recovery and outcomes after device implantation.

Visits at approximately 75 days, 6 months, and 12 months post-operative

Trial Site Locations

Total: 16 locations

1

Gulf Orthopedics

Mobile, Alabama, United States, 36604

Completed

2

Cedars-Sinai Medical Center

Los Angeles, California, United States, 90048

Actively Recruiting

3

Presbyterian St Luke's Medical Ctr

Denver, Colorado, United States, 80218

Actively Recruiting

4

University of Miami Hospital

Miami, Florida, United States, 33136

Actively Recruiting

5

Weston Outpatient Surgical Center

Weston, Florida, United States, 33326

Actively Recruiting

6

Parkview Health

Fort Wayne, Indiana, United States, 46845

Withdrawn

7

Jacobi Medical Center

The Bronx, New York, United States, 10461

Actively Recruiting

8

Mission Hospital

Asheville, North Carolina, United States, 28801

Withdrawn

9

Wake Forest Baptist Health

Winston-Salem, North Carolina, United States, 27157

Actively Recruiting

10

Temple University Hospital

Philadelphia, Pennsylvania, United States, 19140

Actively Recruiting

11

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States, 15232

Actively Recruiting

12

Ortho Rhode Island

Wakefield, Rhode Island, United States, 02879

Actively Recruiting

13

Memorial Hermann Hospital

Katy, Texas, United States, 77494

Actively Recruiting

14

St Vinzenz Hospital

Cologne, Germany

Withdrawn

15

Johannes Wesling Hospital Minden

Minden, Germany

Completed

16

Petrus Hospital

Wuppertal, Germany

Completed

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Research Team

L

Lisa Holt, PhD

C

Caitlin Smith, MPH

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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