Actively Recruiting
Study of Dexamethasone, Olanzapine, and Different Heart Pump and Lung Ventilation Methods in Adults Undergoing On-pump Heart Surgery
Led by Rigshospitalet, Denmark · Updated on 2025-04-04
1200
Participants Needed
1
Research Sites
8 weeks
Total Duration
AI-Summary
What this Trial Is About
Researchers are investigating the effects of four different interventions in adults undergoing open heart surgery, including coronary artery bypass grafting CABG andor aortic valve replacement AVR. The goal is to study how these interventions impact the number of days patients are alive and out of the hospital within 90 days after surgery. This randomized clinical trial addresses risks of mortality and organ injury associated with cardiac surgery and cardiopulmonary bypass CPB. The study evaluates important factors like inflammation, organ perfusion, and lung protection during surgery.
CONDITIONS
Brief Title
Dexamethasone, Olanzapine, Hemodynamics, and Ventilation in Cardiac Surgery
Research Team
S
Sebastian Wiberg, MD, PhD
C
Christian Hassager, MD, DMSc
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