Actively Recruiting
Dexamethasone Use in Pediatric Rhabdomyolysis Patients in Addition to Standard Protocols
Led by Children's National Research Institute · Updated on 2025-07-03
50
Participants Needed
1
Research Sites
117 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
There is a significant unmet need for optimized treatment in rhabdomyolysis. There are few prospective interventional studies on treatment for rhabdomyolysis, a condition which affects diverse and underrepresented populations at a higher rate. While steroids are often used off-label, a systematic study has not yet been initiated, and steroids have not been yet considered in as a consideration to standard care guidelines. The hypothesis is that patients who receive dexamethasone in addition to standard care versus placebo and standard care will have improvement in pain, length of hospital stay, and decrease in kidney complications.
CONDITIONS
Official Title
Dexamethasone Use in Pediatric Rhabdomyolysis Patients in Addition to Standard Protocols
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of rhabdomyolysis with creatine kinase over 5000 and trauma excluded
- Ability of parents or patients to understand and willingness to sign written informed consent
- Patients aged 12 years and older must sign written assent
You will not qualify if you...
- Currently taking systemic steroids
- Inability to comply with study instructions
- Uncontrolled illness or psychiatric/social conditions limiting compliance
- Pregnant women (urine pregnancy test required if applicable)
- Gestational age below 40 weeks
- Allergy to fluconazole, clotrimazole, or nystatin
- Unable to tolerate oral medications
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Childrens National
Washington D.C., District of Columbia, United States, 20010
Actively Recruiting
Research Team
N
Natasha Shur, MD
CONTACT
N
Natasha Shur, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
Not the Right Trial for You?
Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.
Already have an account? Log in here