A comparative study of the antiemetic efficacy of dexamethasone, ondansetron, and metoclopramide in patients undergoing gynecological surgery.
Tugsan Egemen Bilgin, Handan Birbicer, Zeliha Ozer...
https://pubmed.ncbi.nlm.nih.gov/20581776Actively Recruiting
Phase Not Applicable
Age: 40Years - 80Years
All Genders
ID07086118
Efficacy of Dexamethasone Versus Metoclopramide for Prophylaxis of Nausea and Vomiting After Cataract Surgery: A Double-blind Randomized Controlled Study
Led by Alexandria University · Updated on 2025-07-25
210
Participants Needed
1
Research Sites
13 weeks
Total Duration
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AI-Summary
What this Trial Is About
Postoperative nausea and vomiting (PONV) is a common consequence of ambulatory surgery, affecting up to 80% of high-risk patients and 20-30% overall. Despite being widespread, a prior survey found that patients are more averse to PONV than pain and other significant postoperative problems. Furthermore, even mild cases of PONV can have serious repercussions, such as postanesthesia care unit (PACU) workflow disruption, delayed discharges, higher medical costs, and lower patient satisfaction.PONV following intraocular surgery can be unpleasant and may lead to serious complications including suprachoroidal hemorrhage (SCH). SCH is a potentially serious condition that occurs when the posterior ciliary arteries or vortex veins burst, resulting in blood in the suprachoroidal region. The hypothesis is that dexamethasone will lower the incidence of PONV after cataract surgery when compared with metoclopramide.
CONDITIONS
Brief Title
Dexamethasone Versus Metoclopramide for Prophylaxis of Nausea and Vomiting After Cataract Surgery
Who Can Participate
Age: 40Years - 80Years
All Genders
Eligibility Criteria
You may qualify if you...
- Age: 40-80 years, both sexes.
- ASA physical status class I to III.
You will not qualify if you...
- history of motion sickness
- patients with gastrointestinal disorders or gastro-oesophageal reflux
- patients taking medications with known antiemetic activity
- previous postoperative vomiting
- allergy to bupivacaine
- allergy to metoclopramide or dexamethasone
AI-Screening
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1
2
3
Trial Site Locations
Total: 1 location
1
Alexandria University
Alexandria, Egypt
Actively Recruiting
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Research Team
S
sarah m elgamal, MD
M
moutaz ghandour, MD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
QUADRUPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
3
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