Actively Recruiting
Study of Dexmedetomidine Added to Bupivacaine for Pain Relief After Knee Arthroscopy in Adults
Led by Al-Azhar University · Updated on 2025-04-22
75
Participants Needed
2
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
This research aims to compare the pain-relieving effects of adding dexmedetomidine to bupivacaine versus bupivacaine alone after knee arthroscopy, specifically in patients undergoing anterior cruciate ligament ACL reconstruction. The study is a prospective, double-blind trial involving 75 patients at Al Azhar University Hospital, focusing on improving postoperative pain management. Participants are randomly assigned to one of three groups a control group receiving 18 ml of normal saline injected into the knee joint, a group receiving 18 ml of 0.25% bupivacaine injected intra-articularly, and a group receiving dexmedetomidine at 1 mcgkg added to the bupivacaine injection. All injections are administered through the arthroscope by the surgeon after completing the procedure. During the study, pain levels will be assessed using the visual analog scale VAS at multiple time points after surgery, including 30 minutes, 1, 2, 4, 6, 12, and 24 hours. Researchers will also monitor the total consumption of meperidine, an additional pain medication used if pain exceeds a certain level. Safety and effectiveness of the pain relief methods will be closely evaluated throughout the postoperative period.
CONDITIONS
Brief Title
Dexmedetomidine and Bupivacaine Intra-articular for Postoperative Analgesia After Knee Arthroscopic Surgery
Research Team
M
Mohamed A. Mahmoud, MD
W
Warda D.K. Ali, MD
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