Actively Recruiting
Study of Dexmedetomidine Use During Thyroid Surgery to Reduce Anesthesia Needs and Improve Recovery Quality
Led by Bach Mai Hospital · Updated on 2026-04-15
100
Participants Needed
1
Research Sites
4 weeks
Total Duration
AI-Summary
What this Trial Is About
This research investigates the use of dexmedetomidine, a drug with sedative and pain-reducing properties, to improve the quality of recovery after thyroid surgery. The study focuses on whether using dexmedetomidine throughout the surgery reduces the need for anesthesia and opioids and lessens coughing, agitation, and blood pressure changes during breathing tube removal. The trial takes place in patients aged 18 to 65 undergoing elective thyroid surgery under general anesthesia. Participants are randomly assigned to one of two groups one receiving dexmedetomidine along with standard anesthesia, and the other receiving standard anesthesia alone. The dexmedetomidine group gets a loading dose before anesthesia induction followed by continuous infusion during surgery. Both groups have anesthesia managed with monitored techniques to maintain proper sedation and muscle relaxation until the breathing tube is safely removed. During the study, patients will be closely monitored for coughing during extubation, anesthetic and opioid use, agitation after waking, heart rate, blood pressure, pain levels, nausea, bleeding complications, and overall recovery quality. These assessments occur during surgery and up to 24 hours afterward. The total participation duration includes surgery and immediate postoperative care to evaluate the drugs impact on recovery.
CONDITIONS
Brief Title
Dexmedetomidine for Improving Emergence Quality in Thyroid Surgery
Research Team
T
Thang Toan Nguyen, MD, PhD, Assoc Prof
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